Obstructive Sleep Apnea and Systemic Hypertension

Cano-Pumarega, Irene; Durán-Cantolla, Joaquín; Aizpuru, Felipe; Miranda-Serrano, Erika; Rubio, Rafael; Martínez-Null, Cristina; Miguel, Javier de; Egea, Carlos; Cancelo, Laura; Álvarez, Ainhoa; Fernandez‐Bolaños, Marta; Barbé, Ferrán

doi:10.1164/rccm.201101-0130oc

Cited by 151 publications

(34 citation statements)

References 37 publications

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“…Two recent prospective longitudinal cohort studies addressed these questions in normotensive subjects and reached opposing conclusions: The first study reported that after adjusting for relevant confounders, OSA was not associated with incident systolic HTN (1180 subjects over 7.5 year mean follow up period). 4 The second study (also from Spain, 1889 participants, 12.2 years of median follow up) identified an increased hazard ratio for incident hypertension in patients with OSA compared to control subjects, and in this second study, the OSA-HTN association remained independent of confounders including age and obesity. Furthermore, follow-up of this patient cohort revealed a dose response relationship between the severity of OSA and the cumulative incidence of HTN (Figure 2).…”

Section: Epidemiological Association Of Osa and Htnmentioning

confidence: 57%

Obstructive Sleep Apnea and Hypertension

2014

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Section: Epidemiological Association Of Osa and Htnmentioning

confidence: 57%

Obstructive Sleep Apnea and Hypertension

2014

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“…In another cohort study, although a significant relationship between hypertension and OSA was identified, the association was diminished after controlling the BMI (36). Results from Victoria sleep cohort study found no association between OSA and incident systemic hypertension in middle-aged adults (37). …”

Section: Discussionmentioning

confidence: 99%

Associations of Alcohol Consumption and Chronic Diseases With Sleep Apnea Among US Adults

Pan

Wang

2014

Int J High Risk Behav Addict

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Background:Sleep apnea (SA) is a common sleep disorder among US adults. Associations of SA with alcohol consumption and some chronic diseases have been inconsistent.Objectives:This study aimed to estimate prevalence of SA and examine its associations with potential factors including alcohol consumption, asthma, diabetes, and hypertension.Patients and Methods:This was a cross-sectional study on 823 adults with SA and 38,638 controls from the 2011 National Survey on Drug Use and Health Data. Weighted univariate and multiple logistic regression analyses were used to examine the associations of SA with the potential factors.Results:The prevalence of SA was higher in males (4.01%) than in females (2.61%), while the prevalence increased with age (0.86%, 3.50%, and 4.47% for age groups of 18-25, 26-64, and ≥ 65, respectively). Univariate analysis revealed that all factors except for income and education were associated with SA (P < 0.05). In multivariable analyses, participants who were current and past alcohol consumers had significantly higher odds of having SA (OR = 1.52, 95% CI = 1.03-2.23; OR = 1.65, 95% CI = 1.09-2.49, respectively) than non-alcohol drinker. Furthermore, asthma (OR = 2.77, 95% CI = 2.04-3.75), diabetes (OR = 2.89, 95% CI = 2.19-3.83), and hypertension (OR = 2.42, 95% CI = 1.91-3.07) were significantly associated with SA.Conclusions:Age, alcohol consumption, asthma, diabetes, and hypertension, were positively associated with SA. More efforts should be directed to promoting screening for SA and finding possible treatments for SA among these vulnerable groups.

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“…Analysis of data from large cohort studies (the Wisconsin Sleep Cohort) 133 showed an association, especially among men, but there remains conflicting evidence (The Sleep Heart Health Study; 159 Vitoria Sleep Study 161 ). Based on these findings and the BP data found in randomised trials, 143 Other cardiovascular inputs to the model are given in Table 41.…”

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confidence: 99%

Clinical effectiveness and cost-effectiveness results from the randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea–hypopnoea (TOMADO) and long-term economic analysis of oral devices and continuous positive airway pressure

Sharples

Glover

Clutterbuck-James

et al. 2014

Health Technology Assessment

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Health Technology Assessment is indexed in MEDLINE, CINAHL, EMBASE, The Cochrane Library and the ISI Science Citation Index and is assessed for inclusion in the Database of Abstracts of Reviews of Effects.This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full HTA archive is freely available to view online at www.journalslibrary.nihr.ac.uk/hta. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Health Technology Assessment journalReports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Technology Assessment are termed 'systematic' when the account of the search appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others. HTA programmeThe HTA programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care.The journal is indexed in NHS Evidence via its abstracts included in MEDLINE and its Technology Assessment Reports inform National Institute for Health and Care Excellence (NICE) guidance. HTA research is also an important source of evidence for National Screening Committee (NSC) policy decisions.For more information about the HTA programme please visit the website: http://www.nets.nihr.ac.uk/programmes/hta This reportThe research reported in this issue of the journal was funded by the HTA programme as project number 08/110/03. The contractual start date was in September 2010. The draft report began editorial review in January 2014 and was accepted for publication in April 2014. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The HTA editors and publisher have tried to ensure the accuracy of the authors' report and would like to thank the reviewers for their constructive comments on the draft document. However, they do not accept liability for damages or losses arising from material published in this report.This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, NETSCC, the HTA programme or the Department of Health. If there are verbatim quotations included in this publication the views and opinions expr...

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Obstructive Sleep Apnea and Systemic Hypertension

Abstract: Our findings do not suggest an association between obstructive sleep apnea and the incidence of SH in the middle-aged general population. Long-term follow-up longitudinal studies are needed to better ascertain this association.

Cited by 151 publications

References 37 publications

Obstructive Sleep Apnea and Hypertension

Obstructive Sleep Apnea and Hypertension

Associations of Alcohol Consumption and Chronic Diseases With Sleep Apnea Among US Adults

Clinical effectiveness and cost-effectiveness results from the randomised controlled Trial of Oral Mandibular Advancement Devices for Obstructive sleep apnoea–hypopnoea (TOMADO) and long-term economic analysis of oral devices and continuous positive airway pressure

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