Obstructive Sleep Apnea Is Associated with Impaired Exercise Capacity: A Cross-Sectional Study

Beitler, Jeremy R.; Awad, Karim M.; Bakker, Jessie P.; Edwards, Bradley A.; DeYoung, Pamela; Djonlagic, Ina; Forman, Daniel E.; Quan, Stuart F.; Malhotra, Atul

doi:10.5664/jcsm.4200

Cited by 56 publications

(68 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Several studies have reported that exercise capacity in patients with OSA is not differ registered in healthy subjects (7 these results conflict with many other reports that have described higher maximal V'O2 in non OSA populations (2)(3)(4)(5)(6)22). Reinforcing this last observation, some studies have shown inversely correlated with peak V'O2 during CPET (3,5,22,23).…”

Section: Discussioncontrasting

confidence: 56%

“…In addition, HR recovery after peak exercise is similar in both groups, but patients with severe OSA tend to demonstrate a slower chronotropic Several studies have reported that exercise capacity in patients with OSA is not different from that registered in healthy subjects (7)(8)(9)(10)(11)(12)21). However, these results conflict with many other reports that have described higher maximal V'O2 in non-OSA than in 6,22). Reinforcing this last observation, some studies have shown that AHI is inversely correlated with peak V'O2 during CPET (3,5,22,23).…”

Section: Correlations Between Sleep Register and Cardiopulmonary Exercontrasting

confidence: 56%

“…A person's sex also has an influence on exercise capacity, which could be at least 20%-40% lower in women than in men (15). These variables have not always been considered, however, when interpreting the results of studies that have evaluated exercise capacity in patients with OSA (2)(3)(4)(5)(6)(7)(8)(9)(10)12). Moreover, these reports have included only a small number of women; therefore, their results might not extend to this population.…”

Section: Introductionmentioning

confidence: 89%

See 2 more Smart Citations

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

et al. 2017

View full text Add to dashboard Cite

INTRODUCTION:To study exercise capacity and heart rate (HR) recovery after peak exercise in morbidly obese female patients with obstructive sleep apnoea (OSA). METHODS:Twenty-four morbidly obese female patients (36.17 ± 9.20 years and 45.20 ± 5.41 kg.m diagnosed with OSA underwent cardiopulmonary exercise testing (CPET) for assessment of peak oxygen uptake (V'O2) and heart rate (HR) recovery at 30, 60 a index [AHI] <15 h-1) and moderate-to-severe (AHI RESULTS: For the entire study population, peak V'O2 was 15.58 ± 2.44 ml.min were found between moderate-to-severe and mild OSA (16.11 ± 2.37 vs. 15.19 ± 2.50 ml.min respectively). HR recovery registered at any time after the peak workload also did not differ between both groups. Nonetheless, the percentage of HR decrease at 90 seconds in the patients with moderate-to-severe OSA (p=.073), and it was negatively correlated with the oxygen desaturation index (r =-0.679, p=.044). CONCLUSION:Exercise capacity is not different bet Nevertheless, patients with moderatethose with milder OSA. Finally, the oxygen desaturation index is related to this slower chron Keywords: Obstructive sleep apnoea, Exercise test, Female, Heart rate, Obesity. Received March 20, 2017; Accepted May 11, 2017 Copyright: © 2017 Authors. This is an open License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and sourc credited. Editor: Javier Jareño Cite as: Carpio C., Santiago A., Gómez-Mendieta M., Caballero P., Martín capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrom IBJ Plus 2017 1(1):e0004. Funding: The author(s) declared that no grants were involved in supporting this work. To study exercise capacity and heart rate (HR) recovery after peak exercise in morbidly obese female patients with obstructive sleep apnoea (OSA).four morbidly obese female patients (36.17 ± 9.20 years and 45.20 ± 5.41 kg.m diagnosed with OSA underwent cardiopulmonary exercise testing (CPET) for assessment of peak oxygen uptake (V'O2) and heart rate (HR) recovery at 30, 60 and 90 seconds. Comparisons were made between mild (apnoea severe (AHI ≥15 h-1) OSA.For the entire study population, peak V'O2 was 15.58 ± 2.44 ml.min-1.kg-1. No differences in peak V'O2 severe and mild OSA (16.11 ± 2.37 vs. 15.19 ± 2.50 ml.min respectively). HR recovery registered at any time after the peak workload also did not differ between both groups. Nonetheless, the percentage of HR decrease at 90 seconds of recovery time was almost statistically significantly lower severe OSA (p=.073), and it was negatively correlated with the oxygen desaturation Exercise capacity is not different between patients with mild and moderate -to-severe OSA tend to have a slower HR recovery response to exercise than those with milder OSA. Finally, the oxygen desaturation index is related to this slower chronotropic response.Obstructive sleep apnoea, Exercise test, Female, Heart rate, Obesity.May 11, 2017; Published May 23, 2017...

show abstract

Section: Discussioncontrasting

confidence: 56%

Section: Correlations Between Sleep Register and Cardiopulmonary Exercontrasting

confidence: 56%

Section: Introductionmentioning

confidence: 89%

See 1 more Smart Citation

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Resting metabolic rate (RMR) was investigated in 6 cross-sectional studies comparing values in OSA and controls, in the morning after an overnight fast [38–43]. In four of the six studies, in which the patients and controls were adequately matched for BMI and age [40–42], or just age [38], RMR was significantly higher in OSA vs. controls.…”

Section: Resultsmentioning

confidence: 99%

Obstructive sleep apnea and energy balance regulation: A systematic review

Shechter

2017

Sleep Medicine Reviews

View full text Add to dashboard Cite

SUMMARY Obesity and obstructive sleep apnea (OSA) have a reciprocal relationship. Sleep disruptions characteristic of OSA may promote behavioral, metabolic, and/or hormonal changes favoring weight gain and/or difficulty losing weight. The regulation of energy balance (EB), i.e., the relationship between energy intake (EI) and energy expenditure (EE), is complex and multi-factorial, involving food intake, hormonal regulation of hunger/satiety/appetite, and EE via metabolism and physical activity (PA). The current systematic review describes the literature on how OSA affects EB-related parameters. OSA is associated with a hormonal profile characterized by abnormally high leptin and ghrelin levels, which may encourage excess EI. Data on actual measures of food intake are lacking, and not sufficient to make conclusions. Resting metabolic rate appears elevated in OSA vs. controls. Findings on PA are inconsistent, but may indicate a negative relationship with OSA severity that is modulated by daytime sleepiness and body weight. A speculative explanation for the positive EB in OSA is that the increased EE via metabolism induces an overcompensation in the drive for hunger/food intake, which is larger in magnitude than the rise in EI required to re-establish EB. Understanding how OSA affects EB-related parameters can help improve weight loss efforts in these patients.

show abstract

“…20 Traditionally, maximum oxygen consumption (VO 2 max) has been used to represent the maximum aerobic capacity [1][2] . Presently, VO 2 max is used as an indicator of cardiorespiratory tness [3][4][5][6][7][8] , running performance predictor [6][7][8] , to evaluate training related adaptations in healthy individuals 9 and in patients with coronary arterial disease 10 , detraining [11][12] , mortality predictor 13 and to evaluate sleeping disorder 14 . Thereby, VO 2 max identification is important to evaluate the tness levels in athletes as well as in high-risk groups.…”

Section: Introductionmentioning

confidence: 99%

O platô do VO2max não está associado à capacidade anaeróbia em indivíduos fisicamente ativos

Silva

Silva‐Cavalcante

Azevedo

et al. 2016

Rev. bras. educ. fís. esporte

View full text Add to dashboard Cite

show abstract

Obstructive Sleep Apnea Is Associated with Impaired Exercise Capacity: A Cross-Sectional Study

Cited by 56 publications

References 31 publications

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

Exercise capacity and heart rate recovery response to exercise in morbidly obese female patients with obstructive sleep apnoea syndrome.

Obstructive sleep apnea and energy balance regulation: A systematic review

O platô do VO2max não está associado à capacidade anaeróbia em indivíduos fisicamente ativos

Contact Info

Product

Resources

About