2004
DOI: 10.1097/01206501-200412000-00006
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Occupational Allergic Contact Dermatitis from Antioxidant Amines in a Dental Technician

Abstract: We describe an 18-year-old dental technician who presented with dry hyperkeratotic lesions on his left palm that were limited to an area that was in contact with a container in which he had prepared the molds for a dental prosthesis. On patch testing, he had a positive reaction to black rubber mix and its components N-cyclohexyl-NV-phenyl-4-phenylenediamine, N,NV-diphenyl-4-phenylenediamine, and N-isopropyl-NV-phenyl-4-phenylenediamine, as well as to a piece of the rubber container. Thin-layer chromatography (… Show more

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“…This may cause serious problems due to the known toxicity of aliphatic and aromatic amines (Hughes et al [ 1995 ]; Patnaik [ 2007 ]; Smith [ 2010 ]). There are several examples of contact dermatitis resulting from the use of amine compounds in modified polymers (Conde-Salazar et al [ 2004 ]; Soto et al [ 1989 ]), and also the health problems caused by amine hardeners in epoxy systems have been studied shortly after the introduction of epoxy resins into modern industry (Bourne et al [ 1959 ]). After many years of usage of epoxy resins in different industrial and commercial applications, the problem of health hazards caused by such systems is still not completely examined, although many published works have focused on allergies, caused by both the epoxy resin itself (Akita et al [ 2001 ]; Kumar and Freeman [ 1999 ]; Sasseville [ 1998 ]) as well as resin modifiers, such as hardeners (Bachanek et al [ 2005 ]; Bray [ 1999 ]).…”
Section: Introductionmentioning
confidence: 99%
“…This may cause serious problems due to the known toxicity of aliphatic and aromatic amines (Hughes et al [ 1995 ]; Patnaik [ 2007 ]; Smith [ 2010 ]). There are several examples of contact dermatitis resulting from the use of amine compounds in modified polymers (Conde-Salazar et al [ 2004 ]; Soto et al [ 1989 ]), and also the health problems caused by amine hardeners in epoxy systems have been studied shortly after the introduction of epoxy resins into modern industry (Bourne et al [ 1959 ]). After many years of usage of epoxy resins in different industrial and commercial applications, the problem of health hazards caused by such systems is still not completely examined, although many published works have focused on allergies, caused by both the epoxy resin itself (Akita et al [ 2001 ]; Kumar and Freeman [ 1999 ]; Sasseville [ 1998 ]) as well as resin modifiers, such as hardeners (Bachanek et al [ 2005 ]; Bray [ 1999 ]).…”
Section: Introductionmentioning
confidence: 99%