Occurrence and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus Aureus (Mrsa) in Layer Chickens in Kebbi, Nigeria

Abstract

Antimicrobial resistance (AMR) is a global health threat, and antimicrobial use in animal production for growth enhancement or prophylaxis contributes to the development of AMR. A cross-sectional study was conducted to investigate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in poultry and farm attendants in Kebbi, North-Western Nigeria. A total of 207 cloacal and nasal swabs were randomly collected from four farms comprising 50 samples from each poultry farm and only 7 samples from farm attendants. The samples were analysed using routine bacteriological culture and identification techniques. Presumptive MRSA isolates were confirmed by PCR assay and AMR profiles of the isolates were evaluated using the Kirby-Bauer disk diffusion method. Of the 207 samples examined, 37.5 % (75/200) of layer birds tested positive for MRSA and 71.4 % (5/7) of farm attendants were MRSA positive. All the isolates were susceptible to vancomycin, with an AMR index ˃ 0.3. The findings of this study indicated colonization of layer chickens and humans by multidrug resistant MRSA, thus highlighting the potential role of poultry sources of transmission of multidrug-resistant MRSA strains to humans and vice versa.

Occurrence of Methicillin-resistant Staphylococcus aureus (MRSA) From Dairy Cows in Kebbi, Nigeria

“…All the phenotypically positive MRSA isolates used in this study harbored the mecA gene. This finding agrees with Gaddafi et al (2021) and Gaddafi et al (2022), who reported that all the phenotypic MRSA isolates from livestock and poultry harbored the mecA gene. Furthermore, Umaru et al (2014), Rodrigues et al (2017), andAliyu et al (2020) reported the presence of mecA in phenotypically positive MRSA isolates.…”

Livestock and environment as potential sources and reservoirs for multi-drug resistant Escherichia coli in Malaysia: A Systematic Review

“…Animal feces are recognized as the primary source of pathogenic E. coli. The close proximity between livestock and their environment facilitates the transmission of pathogenic bacteria among animals and between animals and the environment (Gaddafi et al, 2022).…”

“…E. coli is the predominant bacterium associated with bacterial infections in livestock, causing significant health problems, increased mortality, reduced production, and higher costs for disease prevention and treatment. A wide range of antimicrobials is commonly used in livestock production, primarily administered orally, to prevent and treat diseases and enhance growth and productivity (Gaddafi et al, 2022).…”