Occurrence and distribution of carbamazepine, nicotine, estrogenic compounds, and their transformation products in wastewater from various treatment plants and the aquatic environment

Ekpeghere, Kalu I.; Sim, Won-Jin; Lee, Heon-Jun; Oh, Jeong‐Eun

doi:10.1016/j.scitotenv.2018.05.218

Cited by 82 publications

(29 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, the median concentrations of these compounds reached values between 45.8 and 95.6 µg•L −1 during monitoring. This behavior was observed in other studies in which the highest concentrations of pharmaceuticals studied were obtained for these three stimulants as well [24][25][26][27]. Moreover, two anti-inflammatory drugs, naproxen and ibuprofen, also presented median concentrations in the range of µg•L −1 (between 19.9 and 27.3 µg•L −1 ) in influent samples and naproxen showed the highest concentration of all the monitored compounds (521.7 µg•L −1 in an influent sample).…”

Section: Conventional Treatment Wwtpssupporting

confidence: 83%

A Survey of the Presence of Pharmaceutical Residues in Wastewaters. Evaluation of Their Removal using Conventional and Natural Treatment Procedures

et al. 2020

View full text Add to dashboard Cite

To encourage the reutilization of treated wastewaters as an adaptation strategy to climate change it is necessary to demonstrate their quality. If this is ensured, reclaimed waters could be a valuable resource that produces very little environmental impact and risks to human health. However, wastewaters are one of the main sources of emerging pollutants that are discharged in the environment. For this, it is essential to assess the presence of these pollutants, especially pharmaceutical compounds, in treated wastewaters. Moreover, the different treatment processes must be evaluated in order to know if conventional and natural treatment technologies are efficient in the removal of these types of compounds. This is an important consideration if the treated wastewaters are used in agricultural activities. Owing to the complexity of wastewater matrixes and the low concentrations of pharmaceutical residues in these types of samples, it is necessary to use sensitive analytical methodologies. In this study, the presence of 11 pharmaceutical compounds were assessed in three different wastewater treatment plants (WWTPs) in Gran Canaria (Spain). Two of these WWTPs use conventional purification technologies and they are located in densely populated areas, while the other studied WWTP is based in constructed wetlands which purify the wastewaters of a rural area. The sampling was performed monthly for two years. A solid phase extraction (SPE) coupled to ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method was applied for the analysis of the samples, and the 11 pharmaceuticals were detected in all the studied WWTPs. The concentrations were variable and ranged from ng·L−1 in some compounds like diclofenac or carbamazepine to µg·L−1 in common pharmaceutical compounds such as caffeine, naproxen or ibuprofen. In addition, removal efficiencies in both conventional and natural purification systems were evaluated. Similar removal efficiencies were obtained using different purifying treatments, especially for some pharmaceutical families as stimulants or anti-inflammatories. Other compounds like carbamazepine showed a recalcitrant behavior. Secondary treatments presented similar removal efficiencies in both conventional and natural wastewater treatment plants, but conventional treatments showed slightly higher elimination ratios. Regarding tertiary system, the treatment with highest removal efficiencies was reverse osmosis in comparison with microfiltration and electrodialysis reversal.

show abstract

Section: Conventional Treatment Wwtpssupporting

confidence: 83%

A Survey of the Presence of Pharmaceutical Residues in Wastewaters. Evaluation of Their Removal using Conventional and Natural Treatment Procedures

et al. 2020

View full text Add to dashboard Cite

show abstract

“…5, the CAR metabolites acridine and 3-hydroxy carbamazepine were found in the digestate samples, indicating effective transformation in the substrate or during biogas production (AD). Surprisingly, the CAR transformation product carbamazepine-10,11-epoxide, usually identied as the main CAR transformation product in waste water and other biologically active matrices, [70][71][72] was not detected in the digestate samples investigated here.…”

Section: Contaminants Of Emerging Concern In Liquid Digestatesmentioning

confidence: 62%

Organic contaminants of emerging concern in Norwegian digestates from biogas production

Ali

Nesse

Eich‐Greatorex

et al. 2019

Environ. Sci.: Processes Impacts

View full text Add to dashboard Cite

show abstract

“…Before that, it is enzymatically transformed to 10, 11-epoxy-10, 11-dihydro-CBM, and from the hydrolysis of these intermediates, CBZ-diOH is produced. For this reason, CBZ-diOH was one the most abundant CBZ compounds detected in water [8]. CBZ is one of the commonly detected compounds in the effluents.…”

Section: Introductionmentioning

confidence: 99%

“…The CBZ and metabolite removal efficiency was −11-18% toward human waste treatment plants, −40% to 25% in the sewage treatment plants and −100-56% in hospital wastewater treatment plants. The concentration of CBZ in the influent and effluent samples were abnormal, this is due to the fact of the low removal rate of CBZ [8].…”

Section: Introductionmentioning

confidence: 99%

Advanced Oxidation Process for Degradation of Carbamazepine from Aqueous Solution: Influence of Metal Modified Microporous, Mesoporous Catalysts on the Ozonation Process

et al. 2020

View full text Add to dashboard Cite

Carbamazepine (CBZ), a widely used pharmaceutical compound, is one of the most detected drugs in surface waters. The purpose of this work was to identify an active and durable catalyst, which, in combination with an ozonation process, could be used to remove CBZ and its degradation products. It was found that the CBZ was completely transformed after ozonation within the first minutes of the treatment. However, the resulting degradation products, 1-(2-benzaldehyde)-4-hydro-(1H,3H)-quinazoline-2-one (BQM) and 1-(2-benzaldehyde)-(1H,3H)-quinazoline-2,4-dione (BQD), were more resistant during the ozonation process. The formation and degradation of these products were studied in more detail and a thorough catalytic screening was conducted to reveal the reaction kinetics of both the CBZ and its degradation products. The work was performed by non-catalytic ozonation and with six different heterogeneous catalysts (Pt-MCM-41-IS, Ru-MCM-41-IS, Pd-H-Y-12-EIM, Pt-H-Y-12-EIM, Pd-H-Beta-300-EIM and Cu-MCM-41-A-EIM) operating at two temperatures 20 °C and 50 °C. The influence of temperature on degradation kinetics of CBZ, BQM and BQD was studied. The results exhibited a notable difference in the catalytic behavior by varying temperature. The higher reactor temperature (50 °C) showed a higher activity of the catalysts but a lower concentration of dissolved ozone. Most of the catalysts exhibited higher removal rate for BQM and BQD compared to non-catalytic experiments in both temperatures. The Pd-H-Y-12-EIM catalyst illustrated a higher degradation rate of by-products at 50 °C compared to other catalysts.

show abstract

Occurrence and distribution of carbamazepine, nicotine, estrogenic compounds, and their transformation products in wastewater from various treatment plants and the aquatic environment

Cited by 82 publications

References 45 publications

A Survey of the Presence of Pharmaceutical Residues in Wastewaters. Evaluation of Their Removal using Conventional and Natural Treatment Procedures

A Survey of the Presence of Pharmaceutical Residues in Wastewaters. Evaluation of Their Removal using Conventional and Natural Treatment Procedures

Organic contaminants of emerging concern in Norwegian digestates from biogas production

Advanced Oxidation Process for Degradation of Carbamazepine from Aqueous Solution: Influence of Metal Modified Microporous, Mesoporous Catalysts on the Ozonation Process

Contact Info

Product

Resources

About