Occurrence of Serious Bacterial Infections Since Introduction of Antibacterial Agents

Finland, Maxwell; Jones, Wilfred F.; Barnes, Mildred W.

doi:10.1093/infdis/125.supplement_1.s89

Cited by 13 publications

(13 citation statements)

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“…An increase in the number of bacteraemias found in hospital patients in recent years has been reported by Munroe and Cockroft (1955), Finland, Jones, andBarnes (1959), Faber, Jessen, Rosendal, andEriksen (1960), McCabe and Jackson (1962), McHenry, Martin, and Wellman (1962), Maiztegui et al (1965), and Watt and Okubadejo (1967). Most laboratories have been receiving more blood cultures every year.…”

Section: Discussionmentioning

confidence: 82%

Some bacteraemias encountered in hospital practice

Crowley

1970

J Clin Pathol

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This is a retrospective study of the results of 4,642 blood cultures taken from 2,190 patients from 1960 to 1967 in one London hospital. The results suggested that an increased incidence of bacteraemias at this particular hospital was mainly due to the increase in the number of patients having blood cultures. Some of the bacteraemias were terminal or transient and probably of doubtful clinical significance.

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Section: Discussionmentioning

confidence: 82%

Some bacteraemias encountered in hospital practice

Crowley

1970

J Clin Pathol

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“…Other nurseries have reported using antibiotics at a rate of 50-60% (Shallard and Williams, 1966;Farmer, 1968). There is evidence that their widespread use may have brought about changes in bacterial flora and in the host himself, which have increased the opportunities for invasion by usually benign organisms, the majority of them Gramnegative (Finland, Jones, and Barnes, 1959). It seems that the restriction of their use whenever possible may reduce the likelihood of resistant strains appearing (Barber et al, 1960;Bulger and Sherris, 1968).…”

Section: A Tibiotics Treatmentmentioning

confidence: 99%

Bacterial infection in the fetus and newborn.

Davies¹

1971

Archives of Disease in Childhood

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“…An increasing incidence of Gram-negative infection in hospital practice is now a well-recognized phenomenon and antibiotics undoubtedly contribute to this. The increased incidence of Gram-negative bacillaemias since the introduction of antibacterial agents is reported by Denton et al (1957) and Finland, Jones, and Barnes (1959) while others have recorded rapid Gram-negative colonization of various sites (Redman and Lockey, 1967;Mummery, Bradley, and Jeffries, 1971;Devetski, Tillman, Norsen, and Lepper, 1963;Montgomerie, Doak, Taylor, and North, 1970). The resistance of the patient influences the type of organism.…”

Section: Discussionmentioning

confidence: 99%

Bacteraemia after open-heart surgery

Lockey¹,

Gonzalez‐Lavin²,

Ray³

et al. 1973

Thorax

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We have analysed the bacteraemias occurring before discharge from hospital in patients subjected to open-heart surgery. The overall incidence was 2-7%. The predominant organisms at first were staphylococci and streptococci, but in the later years of the study almost all positive blood cultures were due to Gram-negative bacilli. Short-term prophylactic antibiotics were used throughout. Eleven of the 12 Gram-positive bacteraemias occurred after the period of antibiotic prophylaxis; eight of the patients had endocarditis and a further three had serious wound infections. Most of the 32 Gram-negative bacillaemias occurred while antibiotics were being given. Some were transient phenomena in well patients; others were associated with terminal states. Infection was a major cause of death in four patients, however, and two patients had endocarditis. Serratia, providence, hafnia, and citrobacter were all identified as well as the more usual escherichia, klebsiella, and pseudomonas. We discuss the possible origins and management of these bacteraemias.

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Occurrence of Serious Bacterial Infections Since Introduction of Antibacterial Agents

Cited by 13 publications

References 0 publications

Some bacteraemias encountered in hospital practice

Some bacteraemias encountered in hospital practice

Bacterial infection in the fetus and newborn.

Bacteraemia after open-heart surgery

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