Occurrence of the Legionella species in the respiratory samples of patients with pneumonia symptoms from Ahvaz, Iran; first detection of Legionella cherrii

Ghorbani, Atosa; Hashemzadeh, Mohammad; Amin, Mansour; Moosavian, Mojtaba; Nashibi, Roohangiz; Mehraban, Zahra

doi:10.1007/s11033-021-06704-3

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…The next most common etiological agents disease (2-7%) are; L. longbeachae, L. bozemanii and L. micdadei [12, 14]. The first detection of L. cherrii species in the respiratory samples of patients with pneumonia symptoms was published by Atosa Ghorbani et al ., 2021 [15].…”

Section: Introductionmentioning

confidence: 99%

Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water

Valenci,

Ohad,

Robinstein

et al. 2023

Preprint

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Bacteria of the genus Legionella are natural pathogens of the environment that can cause legionellosis, which can result in severe human pneumonia called Legionnaires disease. Here we describe a novel Legionella species isolated from hot water source in Israel. High quality complete genome was generated using a combination of Nanopore and Illumina sequencing approaches. Our novel Legionella isolate possesses a 4,071,709 bp chromosome and a single novel large incF conjugative plasmid of 160,437 bp. Interestingly, the chromosome encodes for 14 secondary metabolites biosynthetic gene clusters, more than any known other Legionella sp. The novel plasmid encodes for multiple genes that confer resistance to heavy metals. Bioinformatics analysis revealed that the genome of the new isolate differs from any previously described Legionella species. The closest related species to our isolate is Legionella cherrii. The name proposed for the new specie is Legionella felix in honor of Dr. Arthur Felix (1887-1956), a pioneering microbiologist, and member of the Royal Society of UK, who established the National Public Health Laboratory in Tel Aviv.

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Section: Introductionmentioning

confidence: 99%

Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water

Valenci,

Ohad,

Robinstein

et al. 2023

Preprint

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The Adequacy of Current Legionnaires’ Disease Diagnostic Practices in Capturing the Epidemiology of Clinically Relevant Legionella: A Scoping Review

Ha,

Heilmann,

Lother

et al. 2024

Pathogens

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Legionella is an underdiagnosed and underreported etiology of pneumonia. Legionella pneumophila serogroup 1 (LpSG1) is thought to be the most common pathogenic subgroup. This assumption is based on the frequent use of a urinary antigen test (UAT), only capable of diagnosing LpSG1. We aimed to explore the frequency of Legionella infections in individuals diagnosed with pneumonia and the performance of diagnostic methods for detecting Legionella infections. We conducted a scoping review to answer the following questions: (1) “Does nucleic acid testing (NAT) increase the detection of non-pneumophila serogroup 1 Legionella compared to non-NAT?”; and (2) “Does being immunocompromised increase the frequency of pneumonia caused by non-pneumophila serogroup 1 Legionella compared to non-immunocompromised individuals with Legionnaires’ disease (LD)?”. Articles reporting various diagnostic methods (both NAT and non-NAT) for pneumonia were extracted from several databases. Of the 3449 articles obtained, 31 were included in our review. The most common species were found to be L. pneumophila, L. longbeachae, and unidentified Legionella species appearing in 1.4%, 0.9%, and 0.6% of pneumonia cases. Nearly 50% of cases were caused by unspecified species or serogroups not detected by the standard UAT. NAT-based techniques were more likely to detect Legionella than non-NAT-based techniques. The identification and detection of Legionella and serogroups other than serogroup 1 is hampered by a lack of application of broader pan-Legionella or pan-serogroup diagnostics.

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Occurrence of the Legionella species in the respiratory samples of patients with pneumonia symptoms from Ahvaz, Iran; first detection of Legionella cherrii

Cited by 2 publications

References 27 publications

Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water

Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water

The Adequacy of Current Legionnaires’ Disease Diagnostic Practices in Capturing the Epidemiology of Clinically Relevant Legionella: A Scoping Review

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