Occurrence of the mycotoxins ochratoxin A, zearalenone and deoxynivalenol in feed components

Veldman, A.; Borggreve, G. J.; Mulders, E. J.; Lagemaat, Dick van de

doi:10.1080/02652039209374120

Cited by 35 publications

(15 citation statements)

References 12 publications

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“…This is in contrast to the data reported by Veldman et al (1992), who found all tapioca imported from Thailand and Indonesia to be contaminated with ZEA in the range 17 to 86 μg/kg. The present high incidence of aflatoxins in cassava chip might have originated during the sun-drying of the cassava roots in the field or on the road for at least 2 to 4 days, which is the normal drying technique in Southern Vietnam.…”

Section: Resultscontrasting

confidence: 85%

Screening of Aflatoxins and Zearalenone in feedstuffs and complete feeds for pigs in Southern Vietnam

Thieu

Ogle

Pettersson

2007

Trop Anim Health Prod

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A survey ofaflatoxins and zearalenone (ZEA) in 120 samples, including cassava chip (12), maize (12), rice bran (24), broken rice (24), and complete feeds for growing pigs (24) and sows (24) was carried out in southern Vietnam. Aflatoxin B1 (AFB1), B2 (AFB2), G1 (AFG1) and G2 (AFG2) were determined by an HPLC method using an immunoaffinity column for clean-up. Zearalenone was analysed by Enzyme-Linked Immunosorbent Assay (ELISA) AgraQuant. High incidences of aflatoxins and ZEA in feedstuffs and pig feeds (83.3%-100%) were detected. Aflatoxins and ZEA were detected in all commodities analyzed. Aflatoxin B1 was found in 100, 92, 92, 83, 100 and 96%, respectively, of samples of cassava chip, maize, rice bran, broken rice, and complete feeds for growing pigs and sows, with mean concentrations of 0.86, 77.5, 1.3, 1.6, 4.7 and 7.5 microg/kg, respectively. AFB2 and AFG1 were found in low concentrations and co-occurred with AFB1 in all samples where they were found. ZEA was detected in 8%, 33%, 36%, 21%, 67% and 67%, respectively, of the samples of cassava chip, maize, rice bran, broken rice, and complete feeds for growing pigs and sows, with average concentrations of 10.0, 163.5, 83.1, 31.4, 86.0 and 101.4 microg/kg, respectively. The high incidence of mycotoxins found in feedstuffs highlights the need for periodic monitoring and prevention ofmycotoxins, not only in feeds, but also in food for human consumption.

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Section: Resultscontrasting

confidence: 85%

Screening of Aflatoxins and Zearalenone in feedstuffs and complete feeds for pigs in Southern Vietnam

Thieu

Ogle

Pettersson

2007

Trop Anim Health Prod

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“…1) is one of the most active endocrine disruptors [30]. ZEN is a mycoestrogen with non-estrogenic chemical structure which is produced by several species of Fusarium fungi, and it widely contaminates agricultural products [31] such that ZEN exists in almost all agricultural crops [32]. After consumption, ZEN is metabolized to provide two major stereo isomers, a-and b-zearalenol [33,34], the a-metabolite displaying the highest estrogenic activity [30].…”

Section: High Affinity Xenoestrogensmentioning

confidence: 99%

A structural view of nuclear hormone receptor: endocrine disruptor interactions

Maire

Bourguet

Balaguer

2010

Cell. Mol. Life Sci.

114

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Endocrine-disrupting chemicals (EDCs) represent a broad class of exogenous substances that cause adverse effects in the endocrine system by interfering with hormone biosynthesis, metabolism, or action. The molecular mechanisms of EDCs involve different pathways including interactions with nuclear hormone receptors (NHRs) which are primary targets of a large variety of environmental contaminants. Here, based on the crystal structures currently available in the Protein Data Bank, we review recent studies showing the many ways in which EDCs interact with NHRs and impact their signaling pathways. Like the estrogenic chemical diethylstilbestrol, some EDCs mimic the natural hormones through conserved protein-ligand contacts, while others, such as organotins, employ radically different binding mechanisms. Such structure-based knowledge, in addition to providing a better understanding of EDC activities, can be used to predict the endocrine-disrupting potential of environmental pollutants and may have applications in drug discovery.

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“…OTA is also immunosuppressive resulting in higher susceptibility to subclinical infections (Veldman et al 1992). DON causes feed refusal, emesis and growth depression on swine (Vesonder et al 1976).…”

Section: Introductionmentioning

confidence: 99%

Co-occurrence of mycotoxins in swine feed produced in Portugal

Almeida¹,

Martins

Santos

et al. 2011

Mycotox Res

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A total of 404 samples of commercial swine feed from Portugal feed mills were analysed by HPLC methods for the presence of mycotoxins: 277 samples of feed for fattening pigs were analysed for ochratoxin A (OTA), zearalenone (ZEA), and deoxynivalenol (DON), and 127 samples of feed for sows were analysed for ZEA and fumonisins (FB1 + FB2). Concerning feed for fattening pigs, 21 (7.6%) samples were positive for OTA, (2-6.8 μg/kg), 69 (24.9%) were positive for ZEA (5-73 μg/kg), and 47 (16.9%) were positive for DON (100-864 μg/kg). In feed for sows, the results showed 29.9% of positive samples for ZEA (5-57.7 μg/kg) and 8.7% positive samples for FB1 and FB2 (50-391.4 μg/kg). Co-occurrence of DON/ZEA was found most frequently, but simultaneous contamination with OTA/ZEA and OTA/DON was also found.

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Occurrence of the mycotoxins ochratoxin A, zearalenone and deoxynivalenol in feed components

Cited by 35 publications

References 12 publications

Screening of Aflatoxins and Zearalenone in feedstuffs and complete feeds for pigs in Southern Vietnam

Screening of Aflatoxins and Zearalenone in feedstuffs and complete feeds for pigs in Southern Vietnam

A structural view of nuclear hormone receptor: endocrine disruptor interactions

Co-occurrence of mycotoxins in swine feed produced in Portugal

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