Ocorrência de leishmaniose tegumentar em cães de área endêmica no Estado do Paraná

Pittner, Elaine; Voltarelli, E.; Perles, T. F.; Arraes, Sandra Mara Alessi Aristides; Silveira, Thaís Gomes Verzignassi; Lonardoni, Maria Valdrinez Campana

doi:10.1590/s0102-09352009000300006

Cited by 8 publications

(10 citation statements)

References 18 publications

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“…Large numbers of dogs seropositive for Leishmania spp. have been documented in this state, with a rate of 38.73% (67/173) recorded in the municipality of Umuarama (GERÔNIMO et al, 2014), 18.2% (24/132) in Jussara and Terra Boa (SILVEIRA et al, 1996), 19% (24/126) in Mariluz (LONARDONI et al, 2006), 6.6% (11/169) in Cianorte (CERINO et al, 2010), 45.4% (222/489) in Bela Vista do Paraíso (REIS et al, 2011), and 55.2% (37/67) (ZANZARINI et al, 2005) and 24% (12/50) (PITTNER et al, 2009) in the Maringá region. Such high estimates stress that elevated seropositivity is due to the region's ecosystem and its status as an area endemic for American CL in humans.…”

Section: Resultsmentioning

confidence: 99%

“…Dogs can harbor high levels of parasitism, favoring infection of sand flies (DINIZ et al, 2008). The role of canines in the CCL chain of infection remains an active area of research; however, it has been observed that in areas endemic for the human form of this disease, dogs are also infected with protozoa (FALQUETO et al, 1986;PITTNER et al, 2009). …”

Section: Introductionmentioning

confidence: 99%

“…However, this approach has been questioned because in endemic areas, cases of CVL have increased despite continued efforts to control epidemics. Regarding CL, canine euthanasia is not recommended, owing to a lack of studies concerning the actual role of dogs as a reservoir of the disease (WHO, 2010) Clinical manifestations of VL are similar in dogs and humans, and include non-specific signs, such as irregular fever over long periods, anemia, progressive weight loss, and cachexia in its final stages (PUMAROLA et al, 1991). As the infection and disease progress, many dogs exhibit clinical signs including alopecia, scaling and ulcers, weight loss, increased serum liver enzyme activity, and elevated urea and creatinine levels (CIARAMELLA et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

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Presence of antibodies against Leishmania spp. in domestic dogs from Toledo, Paraná, Brazil

Ludwig

Hernandes

Holsbach

et al. 2016

SCA

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Leishmaniases are a group of diseases caused by Leishmania protozoa affecting various vertebrate hosts, including humans and dogs. Dogs represent the most important domestic reservoir of leishmaniasis. For this reason, the aim of this study was to detect the presence of antibodies against Leishmania spp. in dogs being treated at the veterinary hospital of our institution. Samples were obtained from 175 animals by jugular or cephalic venipuncture, and serum was subsequently separated. Anti-Leishmania spp. IgG antibodies were detected in these specimens using indirect immunofluorescence. This revealed that of the 175 serum samples, those of four (2.28%) animals reacted positively and the antibodies title was 40. These data are consistent with the transmission of Leishmania spp. in the region, suggesting that dogs represent a reservoir of American cutaneous leishmaniasis. This is the first description of circulating antibodies against Leishmania spp. in the West region of Paraná State. Key words: Serological reaction. Leishmaniasis. Canine population. Toledo-PR. ResumoAs leishmanioses são doenças causadas pelo protozoário Leishmania e acometem vários hospedeiros vertebrados, incluindo humanos e cães. Cães representam o reservatório doméstico mais importante da leishmaniose. O objetivo do presente trabalho foi detectar a presença de anticorpos contra Leishmania spp. em cães atendidos na rotina de animais de companhia do Hospital Veterinário desta instituição de ensino. Amostras de sangue de 175 animais foram obtidas por venopunção jugular ou cefálica com posterior obtenção dos soros. Estas amostras foram submetidas à reação de imunofluorescência indireta para detecção de anticorpos da classe IgG anti-Leishmania. A reação sorológica dos 175 soros realizados revelou quatro (2,28%) animais reagentes com título 40. Estes dados revelam a presença de espécies de Leishmania spp. circulando na região, sugerindo o papel de cães como reservatórios para leishmaniose cutânea americana. Esta é a primeira descrição da circulação de anticorpos contra Leishmania spp. na região Oeste do Paraná. Palavras-chave: Reação sorológica. Leishmaniose. População canina. Toledo-PR.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Presence of antibodies against Leishmania spp. in domestic dogs from Toledo, Paraná, Brazil

Ludwig

Hernandes

Holsbach

et al. 2016

SCA

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“…Zulpo et al (2012) and Caldart et al (2015) studied animals from Londrina and found 11.6% (13/112) and 1.2% (3/236) of seropositivity using IFAT method with 1:40 as a cutoff, respectively; the low prevalence of 1.2% found by the authors may be explained because this study population consisted of clinically healthy animals undergoing elective castration surgery. Pittner et al (2009) (CASTRO et al, 2007;PEREIRA, 2005, HOFFMANN et al, 2012. Several phlebotomine species are present in the same State, and the dominant vector species found infected is Nyssomyia whitmani (MEMBRIVE et al, 2004;OLIVEIRA et al, 2000) wich is involved in the transmission of L. (V.) braziliensis; however, L. (L.) amazonensis vectors have never been found in Paraná.…”

Section: Discussionmentioning

confidence: 99%

Leishmaniasis in dogs from recycling centers and from a neighborhood with adjacent forest in an urban area of Londrina, Paraná, Brazil

Costa

Caldart

Ruffolo

et al. 2016

SCA

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The leishmaniasis are a group of globally widespread parasitic diseases caused by a protozoa of the genus Leishmania, the state of Paraná accounts for 98% of leishmaniasis human cases in southern Brazil and the dogs might serve as a sentinel of the risk of infection to humans in a given area. The aim of this work was to study the epidemiology of leishmaniasis in dogs residents in two different environments, they are: recycling of solid waste centers (Group 1) and a neighborhood adjacent to a forest (Group 2), both in Londrina, Paraná State, Brazil and to determine epidemiological variables associated to infection in these different realities. Serum samples, randomly collected, from 61 dogs from Group 1 and from 74 dogs from Group 2 were submitted to Indirect Immunofluorescence Antibody Test (IFAT) to research for anti-Leishmania IgG antibodies. Of the 135 dogs analyzed, 13 animals (9.6%) were positive; nine (14.7%) in Group 1 and four (5.4%) in Group 2, the difference between the groups is not statistically significant. These results suggest the presence of the protozoan Leishmania spp. in both environments studied which indicate potential for infection in the human population. Key words: Environment. Leishmaniasis. Marginality. Risk factors. Seroprevalence. ResumoAs leishmanioses são um grupo de doenças parasitárias disseminadas por todo o mundo, causadas por protozoários do gênero Leishmania, o estado do Paraná é responsável por 98% dos casos de leishmaniose em humanos do Sul do Brasil e os cães podem servir como sentinelas para o risco de infecção em humanos em uma dada área. O objetivo desse trabalho foi estudar a epidemiologia da leishmaniose em cães residentes em dois diferentes ambientes, são eles: centros de reciclagem de resíduos sólidos (Grupo 1) e um bairro adjacente a uma floresta (Grupo 2) em Londrina/PR, Brasil e determiner variáveis epidemiológicas asociadas à infecção nessas diferentes realidades. Amostras de soro, randomicamente coletadas, de 61 cães do Grupo 1 e de 74 cães do Grupo 2 foram submetidos à Reação de Imunofluorescência Indireta (RIFI) para pesquisa de anticorpos IgG anti-Leishmania. Dos 135 cães analisados, 13 (9,6%) foram positivos; 9 (14,7%) no Grupo 1 e 4 (5,4%) no Grupo 2, a

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“…O papel do cão na transmissão da LV é bem conhecido, sendo estes animais considerados o principal reservatório da infecção para os humanos (ALVAR; YACTAYO;BERN, 2006). Dentro da cadeia epidemiológica da leishmaniose cutânea o papel do cão é ainda objeto de estudo, no entanto, observa-se que nas áreas endêmicas os cães também apresentam infecção pelo protozoário (FALQUETO et al, 1986;PITTNER et al, 2009).…”

Section: Introductionunclassified

Ocorrência de anticorpos contra Leishmania spp., Neospora caninum E Toxoplasma gondii em soros de cães atendidos no Hospital Veterinário da Universidade Estadual de Londrina-Pr

et al. 2012

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The aim of this study was to detect the presence of IgG antibodies anti-Leishmania spp., Toxoplasma gondii and Neospora caninum in dogs from a Veterinary Hospital from Universidade Estadual de Londrina. Blood samples from 112 animals were obtained by jugular venipuncture to obtain sera. The samples were tested by indirect immunofluorescence to detect antibodies anti-Leishmania spp., anti-N. caninum and anti-T. gondii. Thirteen (11.61%), 25 (22.32%), and 57 (50.89%) samples were positive for Leishmania spp., N. caninum, and T. gondii, respectively. The co-presence of anti-Leishmania spp. and N. caninum was observed in 6 (5.36%), anti-Leishmania spp. and anti-T. gondii in 8 (14.7%), and anti-N. caninum and anti-T. gondii in 18 (16.07%) samples. The co-presence of anti-Leishmania spp., anti-N. caninum and anti-T. gondii was observed in 5 (4.46%) dogs. There was a higher prevalence of Leishmania in Toxoplasma and Neospora positive animals, however, these results were not statistically significant (range p = 0.052 p = 0.06). The dogs have an important role in the epidemiological cycle of these diseases, which are important in animal and public health. The northern state of Paraná is an endemic area for human cutaneous leishmaniasis, therefore, studies should be conducted to uncover the real role of dogs as reservoirs of Leishmania to humans in the state.

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Ocorrência de leishmaniose tegumentar em cães de área endêmica no Estado do Paraná

Abstract: RESUMO

Cited by 8 publications

References 18 publications

Presence of antibodies against Leishmania spp. in domestic dogs from Toledo, Paraná, Brazil

Presence of antibodies against Leishmania spp. in domestic dogs from Toledo, Paraná, Brazil

Leishmaniasis in dogs from recycling centers and from a neighborhood with adjacent forest in an urban area of Londrina, Paraná, Brazil

Ocorrência de anticorpos contra Leishmania spp., Neospora caninum E Toxoplasma gondii em soros de cães atendidos no Hospital Veterinário da Universidade Estadual de Londrina-Pr

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