Ocular allergy and keratoconus

Sharma, Namrata; Rao, Kavita; Maharana, Prafulla K.; Vajpayee, Rasik B

doi:10.4103/0301-4738.116063

Cited by 79 publications

(59 citation statements)

References 14 publications

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“…23,24 Eye rubbing has been postulated as a significant risk factor by several authors. 3,5,7,[25][26][27] However, few studies [8][9][10][11][12][13][14][15] have referred to eye rubbing as the cause of keratoconus; therefore, it has recently attracted attention. Mashor et al 9 reported three patients with Tourette syndrome and asymmetrical or unilateral keratoconus.…”

Section: Discussionmentioning

confidence: 99%

Snake-like Chromatin Cell Protein as an Indicator of Chronic Eye Rubbing in Patients with Keratoconus and Allergic Conjunctivitis

Henríquez¹,

Canorio²,

Maldonado³

et al. 2018

International Journal of Keratoconus and Ectatic Corneal Diseases

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Purpose:To evaluate the presence of snake-like chromatin (SLC) cell protein (related to eye rubbing) in patients with keratoconus or allergic conjunctivitis and in controls. Materials and methods:Prospective experimental study included 193 eyes of 193 patients between January 2015 and July 2016; 86 had a diagnosis of new keratoconus, 88 were controls, and 19 had a diagnosis of allergic conjunctivitis and underwent impression cytology (IC). Specimens were stained with a combination of periodic acid-Schiff (PAS) and Gill's modified papanicolaou stains to detect the presence of SLC cell protein and morphological characterization of dry eye and allergic conjunctivitis. A questionnaire regarding eye-rubbing habits was administered.Results: Of the patients, 56.97% (49/86 eyes) in the keratoconus group, 84.21% (16/19 eyes) in the allergy group, and 10.11% (9/89 eyes) in the control group reported rubbing their eyes. The SLC was detected in 24.41% (21/86), 73.68% (14/19), and 3.37% (3/89) of the keratoconus, allergy, and control groups respectively, who reported rubbing their eyes. In contrast, SLC was detected in 2.32% (2/86), 0% (0/19), and 1.12% (1/89) of the keratoconus, allergy, and control groups respectively, who reported not rubbing their eyes. Conclusion:The presence of SLC cells was higher in keratoconus, allergy, and control group patients who reported rubbing their eyes. Keratoconus is independent of eye-rubbing habits and the presence of SLC cells.

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Section: Discussionmentioning

confidence: 99%

Snake-like Chromatin Cell Protein as an Indicator of Chronic Eye Rubbing in Patients with Keratoconus and Allergic Conjunctivitis

Henríquez¹,

Canorio²,

Maldonado³

et al. 2018

International Journal of Keratoconus and Ectatic Corneal Diseases

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“…In 2002, Lucarelli et al reported another case of corneal ectasia associated with massage for dacryocystoceles [4]. Also eye rubbing has been implicated in the pathogenesis of keratoconus [5][6][7]. These facts lead us to suppose that excessive post-trabeculectomy massage may lead to corneal deformation and even breaks in Descemet membrane, causing stromal and epithelial edema.…”

Section: Discussionmentioning

confidence: 99%

Acute Keratoconus-Like Corneal Hydrops Secondary to Ocular Massage Following Trabeculectomy

Ke¹,

Chen²,

Lin³

2017

J Clin Exp Ophthalmol

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Purpose: To report a case of acute keratoconus-like corneal hydrops in a patient with long-term ocular massage following trabeculectomy. Methods:Case report and review of medical literature. Results:A rare complication of acute keratoconus-like corneal hydrops occurred in a patient following the use of ocular massage to maintain satisfactory aqueous humor filtration after trabeculectomy. The patient had a history of high myopia but denied previous ocular trauma, allergic disease and a family history of keratoconus. Slit-lamp examination demonstrated keratoconus-like corneal hydrops with formation of epithelial microcystic, and intrastromal cleft. He was diagnosed with acute corneal hydrops in the right eye and received intracameral gas (16% perfluoropropane) injection. On 5 months follow-up, the corneal edema was significantly improved. Conclusions:There may be a contributory relationship between the long-term post-trabeculectomy massage and the development of acute corneal hydrops. When prescribing therapeutic massage, patients should be followed up carefully to monitor for unexpected complications.

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“…Additionally, the most important nonsurgical treatment measure is guidance not to rub the eyes, 4,9 along with treatment of ocular allergy and optimization of ocular surface. 19 Visual restoration should be first attempted with spectacles or contact lenses. Often requiring specially designed corneal or scleral lenses, contact lens fitting constitute the most effective treatment option.…”

Section: Editorialmentioning

confidence: 99%