“…Without a measurement of cross-sectional area or vascular resistance, flow cannot be estimated from CDI measurements. Hence, a high flow velocity in a supplying artery does not necessarily reflect high flow, but may also reflect a stenosis or con- References: Regillo et al (1993), , Kay (1995), Rankin et al (1995), Senn et al (1996), Kaiser et al (1997), Cheng et al (2001), Harris et al (2002), Plange et al (2003), Tranquart et al (2003), Cac¸a et al (2004), Martini et al (2005), Kaup et al (2006) References: Regillo et al (1993), Kay (1995), Rankin et al (1995), Baxter & Williamson (1996), Senn et al (1996), Kaiser et al (1997) striction at the site of measurement (Taylor & Holland 1990). One should realize that the PCA data are less reproducible than CRA data.…”