2015
DOI: 10.1016/j.ebiom.2015.05.024
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Ocular pseudoexfoliation syndrome and life span

Abstract: BackgroundTo compare life span of persons with and without ocular pseudoexfoliation syndrome (PES).MethodsThe study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985–86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality information was obtained from The Norwegian Institute of Public Health in 2014, by which time 99% of the participants were deceased.ResultsWhen adjusting for age and gender, life span was not statistically different in persons… Show more

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Cited by 19 publications
(20 citation statements)
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“…; Slettedal et al. ; Svensson & Ekstrom ). Aqueous humour continuously flows into the anterior chamber of the eye at a rate of 2.4 ± 0.6 μ l/min, or 1.0–1.5% of the anterior chamber volume per minute (Brubaker ; Goel et al.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…; Slettedal et al. ; Svensson & Ekstrom ). Aqueous humour continuously flows into the anterior chamber of the eye at a rate of 2.4 ± 0.6 μ l/min, or 1.0–1.5% of the anterior chamber volume per minute (Brubaker ; Goel et al.…”
Section: Introductionmentioning
confidence: 99%
“…All anterior segment structures may be affected by the presence of XFS materials, thus, potentially resulting in several clinical and surgical complications (Ashok Vardhan et al 2017;Erkayhan & Dogan 2017;Ilveskoski et al 2018;Kurt & Yas ßar 2018). Although not believed to increase mortality, XFS is thought to impair normal eye functions (Ringvold et al 1997;Shrum et al 2000;Grodum et al 2004;Slettedal et al 2015;Svensson & Ekstrom 2015). Aqueous humour continuously flows into the anterior chamber of the eye at a rate of 2.4 AE 0.6 ll/ min, or 1.0-1.5% of the anterior chamber volume per minute (Brubaker 1991;Goel et al 2010).…”
Section: Introductionmentioning
confidence: 99%
“…Finally, and perhaps most importantly, is PES a systemic disease that shortens life expectancy? This is what Slettedal et al (2015) from Norway, a country with a long tradition of PES research, address in this issue of EBioMedicine.…”
mentioning
confidence: 79%
“…The authors conducted in 1985–1986 an epidemiological survey covering 1888 of the 2109 inhabitants older than 64 years in three Norwegian municipalities and determined by biomicroscopy whether they were PES-positive ( Ringvold et al, 1988 ). They returned to this cohort in 2014 by which time 99% of their subjects had died, and requested their dates of death ( Slettedal et al, 2015 ). The authors found no difference in all-cause mortality: the relative risk of death for PES-positive subjects, adjusting for gender and age, was 1.01 and the median life spans of PES-positive and PES-negative subjects were similar in all age groups studied.…”
mentioning
confidence: 99%
“…Das Exfoliationsmaterial wird von intra-und extraokulären Zelltypen (Linsen-, Ziliarkörper-, Irispigmentepithel; Hornhaut-/Trabekelendothel; vaskuläre Endothelzellen, glatte Muskelzellen, Fibrozyten) produziert, sodass es sich um eine stressinduzierte generalisierte Elastose mit höchster Morbidität am Auge handelt. Trotz bekannter Assoziationen mit koronarer Herzerkrankung, arterieller Hypertonie, zerebrovaskulären Erkrankungen, abdominellem Aortenaneurysma, peripheren Gefäßerkrankungen, erektiler Dysfunktion, alzheimerähnlicher Demenz und sensorineuralem Hörverlust ist kein lebenszeitverkürzender Effekt bei Patienten mit PEX nachweisbar [14].…”
Section: Sekundärglaukome Bei Augenerkrankungenunclassified