Odontogenic Keratocyst in Children: A Review

Kamil, Ahmed H.; Tarakji, Bassel

doi:10.2174/1874210601610010117

Cited by 10 publications

(20 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Keratocysts in syndromic patients can present, on average, five per patient, in addition to a higher recurrence rate after enucleation compared to non-syndromic patients. Because of this, it is recommended follow-up for a long period (annually for five years and biannually, for the entire life of the patient) [7,11,20]. Khaliq, et al [11] when evaluating seven syndromic patients, found that all had multiple keratocysts as the first manifestation of the syndrome, most of which were located in the mandible (77%), in an unilocular pattern (71%), associated with teeth (88%).…”

Section: Discussionmentioning

confidence: 99%

Gorlin-Goltz Syndrome: A Case Report

de¹,

Santos²,

Gomes³

et al. 2021

Archives Oral Maxillofac Surg

View full text Add to dashboard Cite

Nevoid basal cell carcinoma syndrome usually presents as an autosomal dominantly inherited syndrome with variable phenotypic expression. The aim of this study was to report a case of this syndrome based on clinical, radiographic, and histopathological findings. Male patient, 13-years-old, attended the Oral Diagnostic Clinic from State University of Paraiba, complaining of mandible swelling. On physical examination, left facial asymmetry was found, with mandible swelling and inflammatory submandibular lymphadenopathy. The patient also presented polydactyly. Panoramic radiography showed a multilocular well-defined mandibular radiolucency in anterior region. An incisional biopsy was performed, confirming the diagnosis of odontogenic keratocyst. Skull postero-anterior and thorax radiographic images were also performed, with no alterations. The patient was clinically diagnosed as having nevoid basal cell carcinoma syndrome with the presence of odontogenic keratocyst as a major criterion and the following minor criteria: Polydactyly, hypertelorism, Sprengel anomaly, deformed chest and prominent frontal bossing. The patient was referred to the physician for evaluation. Nevoid basal cell carcinoma syndrome has several distinct clinical characteristics and careful investigation is important, especially using imaging tests as complementary exams.

show abstract

Section: Discussionmentioning

confidence: 99%

Gorlin-Goltz Syndrome: A Case Report

de¹,

Santos²,

Gomes³

et al. 2021

Archives Oral Maxillofac Surg

View full text Add to dashboard Cite

show abstract

“…Removal of the whole cyst completely, with extraction of the teeth or tooth buds involved by the lesion, is a radical surgical treatment that gives the smallest percentage of relapses. However, if it is possible to preserve the teeth, considering the functional, aesthetic, and psychological aspects, the methods of conservative surgical treatment should be used as the method of choice [3,12,13]. The two-stage method of enucleating a cyst has been successfully used in the Department of Oral Surgery.…”

Section: Discussionmentioning

confidence: 99%

“…The percentage of cases cured was 88.1% and 82.2%, respectively, with a 5-year observation period [14]. In patients treated at developmental age, follow-up examinations are recommended every 6 months [13]. In the case of the above-mentioned patient, the recurrence occurred approximately after 7 years from the moment of diagnosing and starting the two-stage treatment.…”

Section: Discussionmentioning

confidence: 99%

Interdisciplinary surgical and orthodontic treatment of odontogenic keratocyst of the mandibular body in a 12-year-old female patient, with a relapse after 7 years of observation: a case report

Rączkiewicz¹,

Parchańska-Kowalik²,

Stós³

et al. 2018

jos

View full text Add to dashboard Cite

Odontogenic keratocyst, until recently known as keratocystic odontogenic tumor, is a developmental, odontogenic cyst originating from a dental follicle. It is characterized by aggressive and quite fast growth, with a high tendency of recurrence (about 62% of cases). The following article presents a full description of interdisciplinary surgical-orthodontic treatment of a patient who, at the age of 12, was diagnosed with a large keratocyst of the medial region of the mandible, including unerupted teeth: 43, 44, and 45. In addition, partial retention of teeth 23 and 35 was found. Surgical treatment was performed using a two-stage method, with a 7-year follow-up period, during which impacted tooth 43 was removed, and teeth 24 and 36 were also removed. During orthodontic treatment, the acrylic plug was placed in the fenestration area, further orthodontically assisted eruption of dislocated by the cyst teeth 44 and 45, with the use of a removable orthodontic appliance and subsequently, the alignment of the upper and lower teeth with fixed appliances. After completion of orthodontic treatment, 7 years after the cyst enucleation, radiological examination was performed, which revealed a circular lesion in the projection of the roots of the lower teeth with a diameter of about 8 mm, suggesting the presence of cyst relapse. The lesion was enucleated, and the result of the histopathological examination confirmed the diagnosis.

show abstract

“…The parakeratin surface typically appears corrugated, the basal layer is well defined and frequently palisaded with hyperchromatic nuclei and focal areas showing reversed nuclear polarity. [3,7,8,41]. OKC's do not cause metastases or lymph node invasion and do not form tumoral masses.…”

Section: Introductionmentioning

confidence: 99%

“…This is an autosomal dominant multisystem disease that leads to multiple OKC's, as well as several nevoid basal cell carcinomas, palmar or plantar pits, calcification of falx cerebri, and skeletal abnormalities. The Gorlin Goltz syndrome is associated with mutations in the PTCH gene situated on 9q22.3-q31, with described mutation rates of 80-90% [1,7,8,16,19,20]. The established treatment modalities for OKC's can be divided into radical and conservative treatment options.…”

Section: Introductionmentioning

confidence: 99%

Large odontogenic keratocyst of the mandible: A combined intra/extra oral approach followed by enucleation

Vercruysse¹,

D'Haeseleire²,

Kunz³

et al. 2019

EDUJ

View full text Add to dashboard Cite

Aim: An odontogenic keratocyst (OKC) of the mandible is a benign intraosseus lesion of odontogenic origin characterized by a high recurrence rate. In this case report, we highlight the challenging diagnosis and propose a potential treatment for an extensive OKC with lingual expansion. Summary: A 26-year-old male with an OKC in the ramus of the right mandible near the second and third molars was treated by a combined intra/extra-oral approach. A reconstruction plate was adapted and fixed by extra-oral submandibular access, followed by intra/extra-orally executed enucleation. Key learning points: The combined intra/extra oral approach seems a reasonable technique for the treatment of similar extensive OKC's in order to avoid pathological fractures as well as guaranteeing total removal of the lesion.

show abstract

Odontogenic Keratocyst in Children: A Review

Cited by 10 publications

References 26 publications

Gorlin-Goltz Syndrome: A Case Report

Gorlin-Goltz Syndrome: A Case Report

Interdisciplinary surgical and orthodontic treatment of odontogenic keratocyst of the mandibular body in a 12-year-old female patient, with a relapse after 7 years of observation: a case report

Large odontogenic keratocyst of the mandible: A combined intra/extra oral approach followed by enucleation

Contact Info

Product

Resources

About