Odontogenic tumors in Nigerian children and adolescents- a retrospective study of 92 cases

Ajayi, Owolabi; Ladeinde, Akinola Ladipo; Adeyemo, WL; Ogunlewe, M.O.

doi:10.1186/1477-7819-2-39

Cited by 37 publications

(18 citation statements)

References 27 publications

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“…[ 4 ] and Ajayi et al . [ 5 ] This tumor causes gross facial deformity and may result in loss of self-esteem [Figures 1 and 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…This was consistent with the reports in the literature. [ 5 ] Aquilino et al . [ 13 ] noted that the radiologic diagnosis of OFM is sometimes difficult because of variable radiographic characteristics of the different developmental stages.…”

Section: Discussionmentioning

confidence: 99%

“…It occurs mostly in young adults in their second to third decades of life being rare in children <10 years and adults over 50 years. [ 4 5 ] The asymptomatic nature of these lesions encourages late presentation. When very large in the orofacial region, it can cause gross facial disfigurement and functional derangement with specific reference to feeding.…”

Section: Introductionmentioning

confidence: 99%

“…[ 6 7 ] Plain radiographic appearance of OFM may vary from unilocular to multilocular radiolucency with well-defined borders and fine bony trabeculae as a result of bone destruction. [ 5 ] This is often described as “honey comb,” “soap bubble,” “tennis racket,” “wispy”, or “spider web” appearance. [ 1 4 ] Immunohistochemical analysis shows low mitotic activity to Ki-67,[ 8 ] presence of vimentin[ 9 ] and a high concentration of hyaluronic acid.…”

Section: Introductionmentioning

confidence: 99%

“…Varying treatment modalities ranging from curettage to radical excision have been documented. [ 1 5 ] Complete surgical excision, using curettage and peripheral ostectomy alone has been argued to be insufficient treatment as the lesion is not encapsulated. [ 6 ] Due to lack of capsule, a conservative treatment modality may result in infiltration of myxomatous tissue to adjacent bone leading to a high recurrence rate.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Management of odontogenic fibromyxoma in pediatric Nigerian patients: A review of 8 cases

Omeje

Amole

Osunde

et al. 2015

Ann Med Health Sci Res

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Odontogenic fibromyxoma (OFM) is a benign, locally invasive and aggressive nonmetastasizing neoplasm of jaw bones. They are considered relatively rare and known to be derived from embryonic mesenchymal elements of dental origin. Treatment of OFM depends on the size of the lesion and on its nature and behavior. Varying treatment modalities ranging from curettage to radical excision have been documented. Aim; This paper is a review of management of 8 pediatric patients with histologically diagnosed OFM at a Nigerian tertiary health care facility. This was a retrospective study of all patients aged 15 years and below who presented to the Oral and Maxillofacial Surgery Clinic of Aminu Kano Teaching Hospital, Kano, over a 5-year period (January 2008 to December 2012), with a histologic diagnosis of OFM. The information obtained included patients' demographics, as well as their clinical characteristics such as the anatomical site and side of lesions. Other information collated included presenting features, the onset of symptoms, type of treatment carried out, as well as treatment outcome. The data were analyzed and the results presented as frequencies and percentages. Among the 8 patients with OFM, more males (n = 5/8; 62.5%) were affected than females (n = 3/8; 37.5%). The mandible (n = 5/8; 62.5%) was the most frequent site of occurrence, and the anterior mandible was the most favored location (n = 4/8; 50%). Seven patients had excision of the lesion with peripheral ostectomy of the underlying bone while only one patient had a bone resection. These patients have been followed up for at least 1 year, and no recurrence was observed throughout the follow-up period. OFM causes gross facial disfigurement and may result in the destruction of the entire jaw bone; the impact of which may be grave for a growing child. Prompt surgical intervention and follow-up have proven to be adequate management protocol.

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“…[ 4 ] and Ajayi et al . [ 5 ] This tumor causes gross facial deformity and may result in loss of self-esteem [Figures 1 and 2 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%