Ofuji Papuloerythroderma – Pattern

Bettoli, Vincenzo; Mantovani, LG; Malfa, Wilma la

doi:10.1159/000246799

Cited by 10 publications

(10 citation statements)

References 4 publications

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“…In conclusion, we agree with Bettoli et al 2 . that there are cases of papuloerythroderma and ‘deck‐chair sign’ in older people with erythrodermic cutaneous disease of unknown origin; however, we should not use the term ‘Ofuji papuloerythroderma’ when we do not know the aetiology of the dermatosis, and the use of the term ‘papuloerythroderma’ should be limited to cases with sure and appropriate aetiology.…”

Section: To the Editorsupporting

confidence: 88%

Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Camacho

Garcia-Hernandez

Muñoz‐Pérez

et al. 2001

Acad Dermatol Venereol

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Section: To the Editorsupporting

confidence: 88%

Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Camacho

Garcia-Hernandez

Muñoz‐Pérez

et al. 2001

Acad Dermatol Venereol

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“…Several editorials and comments wondered whether PEO was an independent nosographic entity or had rather to be considered a peculiar manifestation pattern of an underlying disease [6,40,104,105,106]. Diseases and triggering factors associated with PEO therefore represent a key topic of analysis.…”

Section: Discussionmentioning

confidence: 99%

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Torchia

Miteva

et al. 2010

Dermatology

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Background: Even after the description of papuloerythroderma of Ofuji (PEO) in 1984, little is known about this clinical entity. Objective:To report on 2 new cases of PEO and review of the worldwide literature on this topic. Methods: Article citations were searched on several biomedical search engines (PubMed, EMBASE, SCOPUS, Google Scholar). Papers were retrieved either online or in print. Results: A grand total of 170 PEO cases were identified. Most patients were older than 55 years and of Asian or white descent, with an overall male/female ratio of 4.0. Itch and the deck-chair sign were observed in all patients. Peripheral eosinophilia, lymphocytopenia and increased serum IgE were common findings. Histopathology mostly showed aspecific inflammation, while 17 showed histological features of cutaneous T-cell lymphoma (CTCL). Atopy, malignancies, infections and drugs were rarely linked to PEO. Conclusion: PEO represents a rather monomorphous entity both clinically and, with the remarkable exception of CTCL, also histologically. Nonetheless, no causative factor could be identified in the vast majority of cases. An etiological classification and diagnostic criteria are proposed in the attempt to contribute framing this puzzling clinical entity.

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“…[5][6][7] Deck-chair sign might be explained as a result from vascular occlusion blocking the efferent arm of the immune reaction. 7,8 Schepers et al . reviewed 26 cases of PED, and described associated signs and symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…10 We also think that the explosive onset, the symmetrical nature of the eruption, the sparing of the skin creases, the intense erythema in the initial phases and laboratory investigations including eosinophilia, lymphopenia, IgE and frequently abnormal protein electrophoresis would all support a circulatory precipitating factor or factors. It is unclear whether PED is a distinctive clinical situation 5,11,12 corresponds to a specific pathological process(a disease) or actually reflects a pattern of expression 1,8,13,14 that many inflammatory dermatoses may take. Many systemic and cutaneous diseases associated with PED were reported including visceral carcinoma (stomach, 15 lung, 15 colon, 9 liver 16 ), T cell & B cell lymphoma, [11][12][13]15 choledocholithiasis, 17 AIDS, 14,18 cutaneous fungal infection, 6 atopic dermatitis 7 and psoriasis.…”

Section: Discussionmentioning

confidence: 99%

Mycosis fungoides presenting as Ofuji's papuloerythroderma

Hur¹,

Jy²,

Ts³

et al. 2002

Acad Dermatol Venereol

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We report three patients presented with clinical features of Ofuji's papuloerythroderma (pruritic erythematous papules and extensive erythema sparing all skin folds), however, showing histopathological findings of mycosis fungoides (Pautrier's microabscess, haloed lymphocytes, disproportionate epidermotropism, and wiry collagen bundles). One case was associated with plaque stage of mycosis fungoides and follicular mucinosis. T-cell receptor (TCR) gene rearrangement analysis in the lesional skin tissue demonstrated rearrangement of the gamma chain in all cases. HTLV-1 serology was negative for two patients who conducted HTLV-1 test. We think that Ofuji's papuloerythroderma might be a variant of early mycosis fungoides rather than secondary skin manifestations to certain cutaneous inflammatory diseases.

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Ofuji Papuloerythroderma – Pattern

Cited by 10 publications

References 4 publications

Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Ofuji papuloerythroderma in an elderly woman with atopic erythroderma

Papuloerythroderma 2009: Two New Cases and Systematic Review of the Worldwide Literature 25 Years after Its Identification by Ofuji et al.

Mycosis fungoides presenting as Ofuji's papuloerythroderma

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