2000
DOI: 10.14341/2072-0351-6197
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Okislitel'naya modifikatsiya belkov pri diabeticheskikh mikroangiopatiyakh

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Cited by 3 publications
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“…Among the causes of diabetic anginopathies development the leading role is given to the raise of platelets functional activity, which molecular mechanism is explained by accumulation of oxygen free radicals that leads to intensification of peroxide oxidation of the lipids of plasma and cellular membranes [16,17]. The reflection of this process is the raise of malonic dialdehyde concentration, where it is a final product of repoxide oxidation of lipids at cyclooxigenase cascade of arachidonic acid in platelet membrane of patients with carbohydrate metabolism concentration [3,18,19]. The increase of glycogen quantity in cellular cytoplasm, the raise of cytoplasmatic Са+ that induces biosynthesis of thromboxane of blood platelets and raises the aggregation activity of platelets take place in platelets membrane of patients with DM as the result of metabolic disorders [20].…”
Section: Materials Of Research and Their Discussionmentioning
confidence: 99%
“…Among the causes of diabetic anginopathies development the leading role is given to the raise of platelets functional activity, which molecular mechanism is explained by accumulation of oxygen free radicals that leads to intensification of peroxide oxidation of the lipids of plasma and cellular membranes [16,17]. The reflection of this process is the raise of malonic dialdehyde concentration, where it is a final product of repoxide oxidation of lipids at cyclooxigenase cascade of arachidonic acid in platelet membrane of patients with carbohydrate metabolism concentration [3,18,19]. The increase of glycogen quantity in cellular cytoplasm, the raise of cytoplasmatic Са+ that induces biosynthesis of thromboxane of blood platelets and raises the aggregation activity of platelets take place in platelets membrane of patients with DM as the result of metabolic disorders [20].…”
Section: Materials Of Research and Their Discussionmentioning
confidence: 99%