Oligosaccharides from land plants and algae: production and applications in therapeutics and biotechnology

Courtois, J.

doi:10.1016/j.mib.2009.04.007

Cited by 159 publications

(110 citation statements)

References 122 publications

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“…Oligosaccharides can be extracted from natural sources or synthesized by physical, chemical or enzymatic methods (Courtois 2009). Commonly employed methods are hydrolysis of polysaccharides or synthesis from disaccharide substrates by enzymatic and chemical treatment (Mussatto and Mancilha 2007).…”

Section: Synthesis and Purification Of Oligosaccharidesmentioning

confidence: 99%

Functional oligosaccharides: production, properties and applications

Patel

Goyal

2010

World J Microbiol Biotechnol

251

123

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Worldwide interest in oligosaccharides has been increasing ever since they were accorded the prebiotic status. The oligosaccharides of various origin like, bacteria, algae, fungi and higher plants have been used extensively both as food ingredients and pharmacological supplements. The non-digestible oligosaccharides have been implicated as dietary fibre, sweetener, weight controlling agent and humectant in confectioneries, bakeries and breweries. Functional oligosaccharides have been found effective in gastrointestinal normal flora proliferation and pathogen suppression, dental caries prevention, enhancement of immunity, facilitation of mineral absorption, source of antioxidant, antibiotic alternative, regulators of blood glucose in diabetics and serum lipids in hyperlipidemics. Apart from the pharmacological applications, oligosaccharides have found use in drug delivery, cosmetics, animal and fishery feed, agriculture, etc. Keeping in view the importance of the functional oligosaccharides, we present an overview of their natural sources, types, structures, physiological properties. Conventional as well as novel synthesis, purification and analysis methods are summarized. Recent promising developments in this area are presented to facilitate their further exploitation.

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Section: Synthesis and Purification Of Oligosaccharidesmentioning

confidence: 99%

Functional oligosaccharides: production, properties and applications

Patel

Goyal

2010

World J Microbiol Biotechnol

251

123

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“…따라서 독성이 없고 피부 투과도가 높은 저분자 히알루론산을 제조하여 세포 외 기질에 히알루론산을 보충함으로써, 피부의 수분 보충 및 탄력저하를 막으려는 노력이 계속되고 있다 [8,10]. 저분자 히알루론산 제조방법에는 산 가수분해 법, 고온가열 방법, 초음파 및 효소를 이용하는 방법 이 있다 [11]. 하지만 상기와 같은 강산을 이용한 가수 분해나 초음파를 이용하는 방법은 단당이 주로 생성 되어 분자의 크기가 균일하지 않고, 고온가열 방법은 변성 가능성 때문에 원하지 않는 부산물이 생길 우려 가 있다 [6,12,13].…”

Section: 서 론unclassified

Effects of Molecular Weights of Sodium Hyaluronate on the Collagen Synthesis, Anti-inflammation and Transdermal Absorption

신은지¹,

박주웅²,

최지원³

et al. 2016

Journal of the Society of Cosmetic Scientists of Korea

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Abstract:In this study, we examined the effects of various molecular weights (1, 10, 50, 100, 660, and 1500 kDa) of sodium hyaluronate (HA), which were prepared by enzyme hydrolysis, on the collagen synthesis, anti-inflammation and skin absorption. These HA did not significantly affect the viability of human dermal fibroblast Hs68 cells. Among them, 1500 kDa, 50 kDa HA most significantly increased collagen production by 59%, and 50% in the Hs 68 cells, respectively. Whereas 1500 and 660 kDa HA hardly pass through mouse transdermis membrane, lower molecular weights (1, 10, or 50 kDa) of HA showed time-dependent increase in skin permeation. HA of 50 kDa showed highest anti-inflammatory effects by reducing nitric oxide and tumor necrosis factor-α production in the RAW 264.7 cells, comparing to other HA (1, 10, and 100 kDa HA). Recently, there is no report about anti-wrinkle and anti-inflammatory effects and skin permeation of different molecular weights HA (1, 10 , 50, 100, 660 and 1500 kDa), which

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“…Oligosaccharides concentration in the different plants ranges between 0.3% and 6% and represent a wide diversity of biomolecules (including stachyose and raffinose), they are chains of monosaccharides that are two to approximately 20 units long. The enzymes belonging to the group of polysaccharide hydrolases (EC 3.2.1.-) which hydrolyse the glycosidic bond between two or more carbohydrates utilize oligosaccharides (Courtois, 2009). …”

Section: Mono-di-and Oligosaccharidesmentioning

confidence: 99%

Digestion in Ruminants

Niwińska¹

2012

Carbohydrates - Comprehensive Studies on Glycobiology and Glycotechnology

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Oligosaccharides from land plants and algae: production and applications in therapeutics and biotechnology

Cited by 159 publications

References 122 publications

Functional oligosaccharides: production, properties and applications

Functional oligosaccharides: production, properties and applications

Effects of Molecular Weights of Sodium Hyaluronate on the Collagen Synthesis, Anti-inflammation and Transdermal Absorption

Digestion in Ruminants

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