2009
DOI: 10.1111/j.1651-2227.2008.01213.x
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Omega‐3 fatty acids, vitamin C and Zn supplementation in asthmatic children: a randomized self‐controlled study

Abstract: Diet supplementation with omega-3 fatty acids, Zn and vitamin C significantly improved asthma control test, pulmonary function tests and pulmonary inflammatory markers in children with moderately persistent bronchial asthma either singly or in combination.

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Cited by 72 publications
(52 citation statements)
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“…Furthermore, lower pre-and post-exercise inflammatory markers in the omega-3 supplement group compared to placebo diets paralleled the changes in EIB severity. These findings of Biltagi et al (2009) and Mickelborough et al (2003, in combination with the present study, demonstrate the broad effectiveness of omega-3 fatty acid supplementation on airway inflammation in the healthy and diseased lung when exposed to inflammatory stress.…”
Section: Discussionsupporting
confidence: 68%
See 1 more Smart Citation
“…Furthermore, lower pre-and post-exercise inflammatory markers in the omega-3 supplement group compared to placebo diets paralleled the changes in EIB severity. These findings of Biltagi et al (2009) and Mickelborough et al (2003, in combination with the present study, demonstrate the broad effectiveness of omega-3 fatty acid supplementation on airway inflammation in the healthy and diseased lung when exposed to inflammatory stress.…”
Section: Discussionsupporting
confidence: 68%
“…Biltagi et al (2009) demonstrated that 6 weeks of omega-3 fatty acid supplementation in asthmatic children significantly reduced sputum markers of airway inflammation with a concomitant improvement in lung function (Biltagi et al 2009). Likewise, colleagues (2003, 2006) determined that 3 weeks of dietary omega-3 fatty acid supplementation decreases the severity of exercise-induced bronchoconstriction (EIB) in both healthy and asthmatic athletes (Mickleborough et al 2006;Mickleborough et al 2003).…”
Section: Discussionmentioning
confidence: 99%
“…In a study in the Islamic Republic of Iran Pouramjad et al showed that zinc supplements had no effect on the clinical manifestations of asthma and on pulmonary function tests (13). In contrast Biltagi et el., in Egypt, showed that consumption of omega-3 fatty acid, vitamin C and zinc, singly or in combination, led to significant improvements in pulmonary function tests and sputum inflammatory markers in placebo, self-controlled trials of children with asthma (14). The aim of the present study in Sari, Islamic Republic of Iran, was to examine the effect of zinc supplementation on clinical symptoms and pulmonary function tests in children with asthma.…”
Section: Introductionmentioning
confidence: 89%
“…173 Recently, the role of ω-3 fatty acids, vitamin C and zinc, either singly or in combination, was evaluated in 60 children with moderately persistent asthma. 174 Childhood asthma control test (C-ACT), pulmonary function tests and sputum inflammatory markers were evaluated at the beginning of the study and at the end of each therapeutic phase. There was significant improvement in the C-ACT, pulmonary function tests and sputum inflammatory markers with diet supplementation for 6 weeks with ω-3 fatty acids, vitamin C and/or zinc.…”
Section: Common Cold Respiratory Tract Infections and Asthmamentioning
confidence: 99%