This paper investigates the completion of the maximal Op*-algebra L + (D) of (possibly) unbounded operators on a dense domain D in a Hilbert space. It is assumed that D is a Frechet space with respect to the graph topology. Let D + denote the strong dual of D, equipped with the complex conjugate linear structure. It is shown that the completion of L + (D} (endowed with the uniform topology) is the space of continuous linear operators X (D, D + ) . This space is studied as an ordered locally convex space with an involution and a partially defined multiplication. A characterization of bounded subsets of D in terms of self-adjoint operators is given. The existence of special factorizations for several kinds of operators is proved. It is shown that the bounded operators are uniformly dense in § 1. Introduction Non-normable topological *-algebras satisfying various completeness conditions have been studied in several papers (see, e.g., [7,8,10,12,22,23,31,34]). However, these conditions are not fulfilled for the maximal *-algebra L + (D] of (possibly unbounded) operators on a dense linear subspace D of some Hilbert space H (for precise definitions, see Section 2). On the other hand, L + (D) is one of the most important unbounded operator algebras because it contains all *-algebras of operators on a fixed domain D.It is the aim of this paper to study the completion of L + (D) with respect to the uniform topology. We assume throughout that D is a Frechet space in the topology defined by the graph norms of operators belonging to L + (D}. However, some of the results can be obtained for more general domains D by the same proofs (see Remark 3 after Proposition 3.8 and the remarks after Proposition 5.1 and Corollary 5.6).Among [24,25]. However, it is closely related to the product of operators on partial inner product spaces which was defined in [3]. Linear spaces with a partially defined multiplication were previously considered also in [4,5,6,11].The pattern of the paper is as follows. In Section 2, we recall some definitions, notations, and some known or easy results. The study of the space JC(D, D + ] will be continued in [21]. In particular, we show there that X(D 9 D + ] is the second strong dual of its subspace of completely continuous operators. In [20, 33], the methods of the present paper are applied to the investigation of closed ideals in L + (D\ Acknowledgements