On a New Continuous Cell Line (TM-1) Derived from Malignant Melanoma

Nishihira, Tetsuro; Kuriya, Yoshiki; Hayashi, Yutaka; Ishii, Hiroshi; Kimura, Michio; Tan, Masaki; Sasaki, Takashi; Kasai, Morio; Katoh, Taizo; Matsuya, Yutaka; Yamane, Isao

doi:10.1620/tjem.128.217

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Cited by 4 publications

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“…In this paper, we report the results of chemotherapy for a patient with esophageal malignant melanoma whose tumor cells were cultured and were subjected to the screening test, and the results of screening test of the cells of cell line TM-1 originated from human skin malignant melanoma which was established in our laboratory (Nishihira et al 1977) .…”

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confidence: 99%

The screening test of various chemotherapeutic drugs in primary malignant melanoma cells and human malignant melanoma cell line (TM-1).

Kuriya

Nishihira

Mori

et al. 1979

Tohoku J. Exp. Med.

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confidence: 99%

The screening test of various chemotherapeutic drugs in primary malignant melanoma cells and human malignant melanoma cell line (TM-1).

Kuriya

Nishihira

Mori

et al. 1979

Tohoku J. Exp. Med.

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Experimental Chemotherapy of Melanoma

Gupta¹

1984

Cancer Treatment and Research

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Establishment, characterization, and response to cytotoxic and radiation treatment of three human melanoma cell lines

et al. 1983

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Three human melanoma cell lines were derived from tumor specimens and established in culture. CAL 1 originated from a bone marrow metastasis and CAL 4 and CAL 7 were derived from solid tumor fragments. CAL 1 and CAL 7 were cloned before establishment. Ultrastructural and chromosome analysis were carried out along with the response to nine chemotherapeutic agents at various concentrations. Survival curves after irradiation were also plotted. The uncloned cell line, CAL 4, displayed some differences from the other two cell lines as regards ploidy and response to chemotherapy. Greater spread of chromosome numbers were observed with this cell line, which contained both hypoploid and a hyperploid modal numbers. All three cell lines showed a relatively high extrapolation number after irradiation, suggesting that inherent cellular properties may be partly responsible for the clinical radioresistance of malignant melanomas.

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On a New Continuous Cell Line (TM-1) Derived from Malignant Melanoma

Cited by 4 publications

References 6 publications

The screening test of various chemotherapeutic drugs in primary malignant melanoma cells and human malignant melanoma cell line (TM-1).

The screening test of various chemotherapeutic drugs in primary malignant melanoma cells and human malignant melanoma cell line (TM-1).

Experimental Chemotherapy of Melanoma

Establishment, characterization, and response to cytotoxic and radiation treatment of three human melanoma cell lines

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