“…3,4,5 In particular, integrated processes have long been recognized to exhibit a dynamic behavior that spans multiple time scales. Many authors 6,7,8,9,10 have indirectly assumed this time scale multiplicity to propose tiered control structures, featuring at least two levels of control action: a primary layer addressing inventory and temperature control at the unit level and providing stability in operation, and a supervisory layer, acting over a slower time scale, that targets the control objectives at the plant level, such as product purity and production rate.…”