On Drug Dosage Control Using Description Defeasible Logic

Hijazi, Sherin; Obeid, Nadim; Jabri, Riad

doi:10.1109/csci.2017.288

Cited by 3 publications

(2 citation statements)

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“…O Use of the design principles of the Open Biomedical Ontology Foundry (OBO). Initial strides were undertaken by Hijazi et al [35] for cultivating a knowledge-based system for proper dosage control of drug to disease treatment. Physicians and pharmacists can be aided by this system when prescribing suitable drugs and their proper dosages.…”

Section: Disease Diagnosis and Treatmentmentioning

confidence: 99%

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On the Logical Foundation of a Personalized Medical Prescription System

2020

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This paper, lays down the logical foundations for a personalized medical prescription system. The proposed system employs detailed pharmaceutical and medical knowledge about a medication and its effects or side effects on the patient, which may go beyond what is available in medication leaflets. The ontology was initially built for the proposed system and employs the description logic system, ALC, for knowledge representation. However, the uncertain nature of medical and medicinal knowledge poses some problems such as drug-drug interactions and drug-disease interactions, which render ALC inadequate to represent and reason within a system such as a personalized medical prescription system. Indeed, there is a need for a more flexible representation that allows reasoning with incomplete knowledge and possibly inconsistent cases. ALC is extended with defeasible rules to obtain defeasible ALC. Defeasible ALC allows the prevention of adverse drug interactions, detection drug-drug interactions and detection of drugdisease interactions. The ultimate purpose of this paper is providing to provide a standard knowledge base system toward a medical prescription capable of dealing with incomplete knowledge, conflicting information (inconsistencies) and exceptions cases, which will enhance individual healthcare and provide an appropriate prescription. This is accomplished by expanding the capabilities of description logic with defeasible rules, to achieve an accurate prescription decision for any patient's condition(s). Once implemented, a personalized medical prescription system intends to assist, not to replace, the clinician during medical prescription(s) or the pharmacist(s).INDEX TERMS Knowledge base system, medical services, medical treatment, health information management, medicine prescription.

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Section: Disease Diagnosis and Treatmentmentioning

confidence: 99%

“…A few extensions of previous medical ontology with defeasible logic can be used to handle incomplete knowledge approach in either limited or universal scope, as in [33] and [35].…”

Section: B Incomplete Knowledge Approachmentioning

confidence: 99%