On Etiopathogenesis of Idiopathic Scoliosis

Abstract

Objectives. To study a role of the central nervous system (CNS) in development of idiopathic scoliosis (IS) and to reveal potential neurophysiologic mechanisms participating in this process. Material and Methods. Electroencephalography (EEG) has been applied to examine patients with IS. For the first time the received data were processed by a mathematical method which allowed to establish the temporal organization of basic brain rhythm formation (α, β, θ). Results. Variants of deviations in functioning of basal structures of the brain and its trunk distinctive for sluggish and rapid progressing forms of IS are revealed. Theoretical description of pathogenetic links of idiopathic three-plane spine deformity formation is suggested. It is proved that a basic condition for its development is a disturbance in longitudinal growth conjugation of the spine bone structures and the spinal cord, which demands certain compensating reactions. Conclusion. Long-term uncontrolled asymmetric change in paravertebral muscle tone is a key link in a clinical formation of IS.

Pathomorphological changes in the structure of intervertebral disc after seven and fourteen days of experimental opioid use

“…A significant percentage of vertebrological pathologies -scoliosis, osteochondrosis, intervertebral hernias, etc., arise as a result of exposure of various factors (hypodynamic, inadequate exercises, metabolic disorders) and manifest by changes of various degrees in the intervertebral discs. [1,[3][4][5].…”