The main intention of the present research study is focused on the analysis of a Caputo fractional integro-differential boundary problem (CFBVP) in which the right-hand side of supposed differential equation is represented as a sum of two nonlinear terms. Under the integro-derivative boundary conditions, we extract an equivalent integral equation and then define new operators based on it. With the help of three distinct fixed-point theorems attributed to Krasnosel’skiĭ, Leray–Schauder, and Banach, we investigate desired uniqueness and existence results. Additionally, the dependence criterion of solutions for this CFBVP is checked via the generalized version of the Gronwall inequality. Next, three simulative examples are designed to examine our findings based on the procedures applied in the theorems.