On-line solid phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry as a powerful technique for the determination of sulfonamide residues in soils

Tetzner, Natália Fernanda; Maniero, Milena Guedes; Rodrigues-Silva, Caio; Rath, Susanne

doi:10.1016/j.chroma.2016.05.034

Cited by 65 publications

(31 citation statements)

References 22 publications

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“…Tetzner et al. evaluated the presence of sulfonamides in soil using SPE–UHPLC–MS/MS. However, once utilizing solid samples, a previous liquid‐solid extraction step was required, using 10 mL of ACN/water (1:1) to 2.0 g soil.…”

Section: Applications Of the On‐line Approach To The Analysis Of Compmentioning

confidence: 99%

“…One of the most successful applications utilizing on-line extraction coupled to chromatographic systems is in the analysis of environmental samples. Tetzner et al [61] evaluated the presence of sulfonamides in soil using SPE-UHPLC-MS/MS. However, once utilizing solid samples, a previous liquid-solid extraction step was required, using 10 mL of ACN/water (1:1) to 2.0 g soil.…”

Section: Applications Utilizing the Switching Valve Approachmentioning

confidence: 99%

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On‐line approaches for the determination of residues and contaminants in complex samples

Fumes

Andrade

Franco

et al. 2016

J of Separation Science

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The determination of residues and contaminants in complex matrices such as in the case of food, environmental, and biological samples requires a combination of several steps to succeed in the aimed goal. At least three independent steps are integrated to provide the best available situation to deal with such matrices: (1) a sample preparation technique is employed to isolate the target compounds from the rest of the matrix; (2) a chromatographic (second) step further "purifies" the isolated compounds from the co-extracted matrix interferences; (3) a spectroscopy-based device acts as chromatographic detector (ideally containing a tandem high-resolution mass analyzer) for the qualitative and quantitative analysis. These techniques can be operated in different modes including the off-line and the on-line modes. The present report focus the on-line coupling techniques aiming the determination of analytes present in complex matrices. The fundamentals of these approaches as well as the most common set ups are presented and discussed, as well as a review on the recent applications of these two approaches to the fields of bioanalytical, environmental, and food analysis are critically discussed.

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Section: Applications Of the On‐line Approach To The Analysis Of Compmentioning

confidence: 99%

Section: Applications Utilizing the Switching Valve Approachmentioning

confidence: 99%

On‐line approaches for the determination of residues and contaminants in complex samples

Fumes

Andrade

Franco

et al. 2016

J of Separation Science

View full text Add to dashboard Cite

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“…In recent years, due to its sensitivity and high throughput capabilities, liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become an attractive and powerful analytical tool for targeted and untargeted analysis of metabolite profiles from many sources, including the soil. Targeted LC-MS soil analysis has focused predominantly on the quantification of soil contaminants hazardous to human health, such as pesticides and herbicides, rocket fuel, polycyclic aromatic hydrocarbons and antibiotics [7][8][9][10][11]. Untargeted analyses, in contrast, have focused on environments less impacted by human activity.…”

Section: Introductionmentioning

confidence: 99%

Local Phenomena Shape Backyard Soil Metabolite Composition

et al. 2020

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Soil covers most of Earth’s continental surface and is fundamental to life-sustaining processes such as agriculture. Given its rich biodiversity, soil is also a major source for natural product drug discovery from soil microorganisms. However, the study of the soil small molecule profile has been challenging due to the complexity and heterogeneity of this matrix. In this study, we implemented high-resolution liquid chromatography–tandem mass spectrometry and large-scale data analysis tools such as molecular networking to characterize the relative contributions of city, state and regional processes on backyard soil metabolite composition, in 188 soil samples collected from 14 USA States, representing five USA climate regions. We observed that region, state and city of collection all influence the overall soil metabolite profile. However, many metabolites were only detected in unique sites, indicating that uniquely local phenomena also influence the backyard soil environment, with both human-derived and naturally-produced (plant-derived, microbially-derived) metabolites identified. Overall, these findings are helping to define the processes that shape the backyard soil metabolite composition, while also highlighting the need for expanded metabolomic studies of this complex environment.

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“…For detecting SAs in food, the analytical technique most widely applied is high-performance liquid chromatography (HPLC), which is combined with different detectors [6,7] including mass spectrometry (MS) [8,9], ultra-violet (UV) [10,11], and fluorescent [12,13] and diode array spectrometers [14]. …”

Section: Introductionmentioning

confidence: 99%

Determination of Sulfonamide Residues in Food by Capillary Zone Electrophoresis with On-Line Chemiluminescence Detection Based on an Ag(III) Complex

Dai

Duan

et al. 2017

IJMS

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The presence of sulfonamide (SA) residues in foods is largely due to the raising of animals with sulfonamide antibiotics added or polluted feedstuff. In this paper, a sensitive method was developed for the determination of the residues of three sulfonamides in animal-derived food; the SAs include sulfadimidine (SDD), sulfadiazine (SDZ), and sulfathiazole (STZ). The method is based on capillary zone electrophoresis (CE) with online chemiluminescence (CL) detection, using an Ag(III) complex as an oxidant. These SAs have an inhibiting effect on the Ag(III)–luminol CL reaction. The electrophoretic buffer is 12.0 mM sodium borate. Under a set of optimized conditions, the linear ranges for the detections were found to be 10.0–200 µg·mL−1 for SDD and SDZ, and 2.0–50.0 µg·mL−1 for STZ. The detection limits were 2.75, 3.14, and 0.65 µg·mL−1 for SDD, SDZ, and STZ, respectively. Relative standard deviations (RSD) for the peak heights were between 2.1% and 2.8% (n = 7). The proposed method was used in the analysis of the SAs in samples from pork meat, chicken meat, and milk, showing satisfactory detection results. A reaction mechanism was also proposed for the Ag(III)–luminol–SA CL reactions. The method has potential applications for the monitoring of residue levels of the three SAs in food, providing food safety data.

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On-line solid phase extraction-ultra high performance liquid chromatography-tandem mass spectrometry as a powerful technique for the determination of sulfonamide residues in soils

Cited by 65 publications

References 22 publications

On‐line approaches for the determination of residues and contaminants in complex samples

On‐line approaches for the determination of residues and contaminants in complex samples

Local Phenomena Shape Backyard Soil Metabolite Composition

Determination of Sulfonamide Residues in Food by Capillary Zone Electrophoresis with On-Line Chemiluminescence Detection Based on an Ag(III) Complex

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