Thrombosis and Haemostasis VTH Congress 1975
DOI: 10.1055/s-0039-1689526
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On Physiological Regulation of the Liquid State and Coagulation of Blood

Abstract: The fluidity of blood in a healthy organism is kept by means of reflex reaction initiated by thrombin appearing in blood stream in a threshold concentration. Heparin and activator of plasminogen are excreting in blood as a result of the reflex act. Heparin forms the complexes with fibrinogen, factors XIII, plasminogen, adrenalin and other factors. These compounds act as antiaggregating and antistabilizing agents on the fibrin monomer. They dissolve non-stabilized fibrin, even in the presence of EACA or antipla… Show more

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Cited by 9 publications
(2 citation statements)
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“…Blood anticoagulant activity was estimated from activated partial thromboplastin time (APTT) [3]. Platelet aggregation was evaluated in platelet-rich plasma after addition of the aggregation-inducing agent (2-5 µM ADP) by measuring optical density of plasma samples on an aggregometer (M. V. Lomonosov Moscow State University).…”
Section: Methodsmentioning
confidence: 99%
“…Blood anticoagulant activity was estimated from activated partial thromboplastin time (APTT) [3]. Platelet aggregation was evaluated in platelet-rich plasma after addition of the aggregation-inducing agent (2-5 µM ADP) by measuring optical density of plasma samples on an aggregometer (M. V. Lomonosov Moscow State University).…”
Section: Methodsmentioning
confidence: 99%
“…The highest/lowest values of SFMCs were detected in carp and the hybrid of A. ruthenus and A. stellatus, respectively. coagulation mechanism is explained by A. Schmidt's enzyme theory and blood coagulation is based on three interrelated phases: thromboplastin formation, thrombin formation, and fibrin formation (Kudryashov, 1975;Amineva & Yarzombek, 1984).…”
Section: Introductionmentioning
confidence: 99%