On the adsorption of magnetite nanoparticles on lysozyme amyloid fibrils

Interaction of Magnetic Nanoparticles with Lyotropic Liquid Crystal Studied by AFM

“…Moreover, the samples remain stable also several weeks after preparation. The obtained results are in good agreement with our previous investigations [13]. Due to the adsorption of magnetic nanoparticles on fibril surface we suggest the possible ordering of the fibrils by applying an external magnetic field that can be helpful in production of biological liquid crystals.…”

“…This technique is capable to provide structural details at the single fibril length scale and via statistical analysis it can yield averages over populations of hundreds to thousands of fibrils. Our preliminary studies of the formation of nematic liquid crystal phase in solutions containing lysozyme amyloid fibrils and magnetic particles of spherical shape by means of transmission electron microscopy (TEM) and small angle X-ray scattering (SAXS) measurements have shown a strong interaction of magnetic nanoparticles with fibril surface [13]. The aim of this work was to apply AFM technique to gain original information about dependence of the interaction of lysozyme fibrils with magnetic nanoparticles on time and on volume concentration.…”

Effect of the concentration of protein and nanoparticles on the structure of biohybrid nanocomposites

“…In addition, the influence of the salt on these composites and colloidal stability has been studied. It was shown that there exists some critical concentration from which nanoparticles start to adsorb on fibril surfaces and form strongly elongated associates in the LAF/MNPs dispersions . Therefore, all MNP concentrations used in this work are from the interval called “adsorption interval” mentioned in our previous work …”

“…In addition, the small size, availability, and outstanding solubility in water make the lysozyme extracted from hen egg white an ideal model of protein to investigate amyloidogenesis and study the interaction of amyloid fibrils with nanoparticles. Experimentally, it has been verified that the adsorption of MNPs on the surface of LAFs depends on the particle concentration and influences the magnetic properties of MNP‐incorporated fibrillary mixture . In a previous research study, it was found that birefringent self‐assembled flower‐like patterns are formed during the evaporation process of the liquid drop of lysozyme fibril/magnetite nanoparticle solution …”

Lysozyme Amyloid Fibrils Doped by Carbon Nanotubes

“…β-strands are arranged perpendicular to the constituent axis while the β-sheets are parallel [4]. It was proved that magnetite nanoparticles can interact with LAF [5]. Since hybrid nanomaterials containing carbon nanotubes may open new strategies in various areas as tissue engineering, biosensors, drug delivery, nanoelectronics and many others, a lot of studies deal with the dispersion of nanotubes in lyotropic liquid crystal (LLC) [6][7][8].…”