On the chemistry of 5‐aryl‐2‐hydrazino‐benzo[6,7]cyclohepta[1,2‐b]pyrido[2,3‐e] pyrimidin‐4‐one

Abstract

Several pyrido[2,3-e]pyrimidine fused with other rings have been prepared by intramolecular cyclization

Synthesis of Some Benzofuranyl Thieno[2,3-D] Pyrimidine Derivatives With Biological Interest

“…Besides some active compounds have been described when the thiophene moiety is fused to carbocyclic ring also, paused heterocyclic pyrimidine nucleosides have synthesized to exhibit prominent and versatile biological activities (4)(5)(6)(7)(8)(9)(10)(11)(12)(13) . The structure of 3 was supported by correct elemental analysis and spectral data.…”

One‐Pot Synthesis of Pyrido[2,3‐d]Pyrimidine‐2‐Thiones and a Study of Their Reactivity Towards Some Reagents

“…5 Our group has been actively working on the development of synthetic strategies for the preparation of 2-thioxopyrido- [2,3-d]pyrimidin-4(1H)-ones. [6][7][8] The present work describes our approach for the synthesis of polyfunctional heterocyclic compounds and convenient methods for the synthesis of triazolopyridopyrimidines 8, 12. Thus, heating 6aminothiouracil 1 with aromatic aldehydes and malononitrile in boiling dimethylformamide for a long time afforded a mixture of 6-(7-amino-5-aryl-2,3-dihydro-2-thioxopyrido [2,3-d]pyrimidin-4(1H)-one) carbonitriles (5ac) (80-75%) and 6-(7-amino-5-aryl-2,3,5,8-tetrahydro-2-thioxopyrido [2,3-d]pyrimidin-4(1H)-one) carbonitriles (3a-c) (25-20%).…”