A pre-natural class of modules over a ring R is one that is closed under isomorphic copies, submodules, arbitrary direct sums, and certain essential extensions. The set p r R of all pre-natural classes is a lattice, which contains many previously studied lattices of R-module classes. The sublattice structure of p r R is studied in this paper and is related to ring and module properties of R © 2000 Academic Press 0. INTRODUCTION Modules are right unital over an arbitrary ring R with identity. For a right R-module N, the injective hull of N is denoted by E N R or simply by EN. For a right R-module M ∈ Mod-R, the trace of M in EN is the module tr M EN = fM f ∈ Hom R M EN . All module classes here will be closed under isomorphic copies. The trace of in EN is the module tr EN = fM M ∈ f ∈ Hom R M EN . A class of modules is a pre-natural class if it is closed under (i) submodules, (ii) arbitrary direct