On the Interdependence of Respiration and Glycolysis

Rosenthal, Otto; Bowie, Morris A.; Wagoner, George

doi:10.1126/science.92.2391.382

Cited by 22 publications

(3 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A probable explanation of this phenomenon is suggested by the results recently reported by Rosenthal et al (1940). These authors showed that in certain tissues possessing the power of aerobic glycolysis, glucose suppresses the respiration in a manner similar to that observed by Crabtree with tumor tissue.…”

Section: Discussionmentioning

confidence: 60%

The Function of Nicotinic Acid in Bacterial Metabolism

Kligler

Grossowicz

1941

J Bacteriol

View full text Add to dashboard Cite

In our previous publications Grossowicz 1938, 1939) we showed that nicotinic acid plays an essential part in the carbohydrate metabolism of certain members of the colon-typhoid group of bacteria-particularly Salmonella paratyphi A, Shigella dysenteriae and some strains of the Flexner type of dysentery. Our results indicated that nicotinic acid was not a growth factor in the limited sense, because growth occurred in its absence, but that it played the part of a codehydrase making available to the organism a source of energy which it could not use in the absence of nicotinic acid.The experiments reported in this paper were designed to test these findings and to account for the apparent contradiction between our results and those reported by Koser in his studies on Shigella paradysenteriae. EXPERIMENTAL MethodsThe same medium was used as in the preceding study. The basic salt mixture was sterilized by filtration through a Seitz filter and a sterile solution of S-K peptone added to give a concentration of 0.3 per cent. This peptone proved useful for these studies because available tests showed that it was free of nicotinic acid, or at any rate that the amount was less than that demonstrable by bacteriologic methods. To this basic medium were added the substances to be tested. Since many of our experiments were made with lactate (which is fermented aerobically) small Erlenmeyer flasks were used instead of test tubes. 173 on July 15, 2020 by guest

show abstract

Section: Discussionmentioning

confidence: 60%

The Function of Nicotinic Acid in Bacterial Metabolism

Kligler

Grossowicz

1941

J Bacteriol

View full text Add to dashboard Cite

show abstract

“…Indications for the oxidations of pyruvic and succinic acids have been previously reported. 3 The experimental results discussed above justify the conclusion that the young cartilage cell is capable of completely oxidising carbohydrate and, possibly, protein. Bywaters in 19361 noted that the addition of methylene blue to equine articular cartilage markedly increased the rate of oxygen consumption.…”

Section: The Properties Of Respiration In Calves' Cartilagementioning

confidence: 63%

Observations on Respiration in Articular Cartilage

Bowie¹,

Rosenthal²,

Wagoner³

1941

Annals of the Rheumatic Diseases

Self Cite

View full text Add to dashboard Cite

“…Finally, in the presence of glucose spermatozoa depend less on oxidative processes for their energy, Spermatozoa are not unique in showing a decrease of respiration in the presence of glucose. This phenomenon has been observed in certain tumors (9, 10, ll), in lymph nodes of leukemic mice (12) and in bovine articular cartilage (13).…”

Section: Sparingmentioning

confidence: 64%