On the necessity of molecular oxygen for the synthesis of respiratory enzymes in yeast

The response by microorganisms to steady state growth in controlled concentrations of oxygen and glucose. I. Candida utilis

“…It seems that glucose, but not galactose, was able to inhibit the formation of complete mitochondria when a minute trace of oxygen was present. 28 Polakis and B a r t l e~~~ relate glucose repression of the pyruvate oxidase system to abundant glucose and have demonstrated, by measurement of ethanol production, that on the other hand glucose induces pyruvic decarboxylase They point out that the high K , value of pyruvic decarboxylase and low value for pyruvic oxidase would cause saturation of the oxidase, which has a low maximum rate, a t low concentrations of pyruvate. In the presence of high glucose and consequently high pyruvate the decarboxylase, which has a high maximum rate, would predominate.…”

Communication Between Mitochondria and the Nucleus in Regulation of Cytochrome Genes in the Yeast Saccharomyces cerevisiae

“…an aerobic growth condition, is clearly required for res piratory growth (Somlo & Fukuhara, 1965). Since oxidative phosphorylation requires O2 as an electron acceptor, the presence of oxygen, i.e.…”

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“…Somlo and Fukuhara, 1965]. Two media were used in this work: medium A containing sucrose, urea, MgS04 and KH2P04 as used by Stich and Eisgruber [1951] and medi um B which contains glucose, (NH4)2S04 and other salts and modified to contain 0.5°/o Difco yeast extract [cf.…”