[1] Energetic electrons (E > 100 keV) in the Earth's radiation belts undergo Dopplershifted cyclotron resonant interactions with a variety of whistler mode waves leading to pitch angle scattering and subsequent loss to the atmosphere. In this study we assess the relative importance of plasmaspheric hiss and lightning-generated whistlers in the slot region and beyond. Electron loss timescales are determined using the Pitch Angle and energy Diffusion of Ions and Electrons (PADIE) code with global models of the spectral distributions of the wave power based on CRRES observations. Our results show that plasmaspheric hiss propagating at small and intermediate wave normal angles is a significant scattering agent in the slot region and beyond. In contrast, plasmaspheric hiss propagating at large wave normal angles and lightning-generated whistlers do not contribute significantly to radiation belt loss. The loss timescale of 2 MeV electrons due to plasmaspheric hiss propagating at small and intermediate wave normal angles in the center of the slot region (L = 2.5) lies in the range 1-10 days, consistent with recent Solar Anomalous and Magnetospheric Particle Explorer (SAMPEX) observations. Wave turbulence in space, which is responsible for the generation plasmaspheric hiss, thus leads to the formation of the slot region. During active periods, losses due to plasmaspheric hiss may occur on a timescale of 1 day or less for a wide range of energies, 200 keV < E < 1 MeV, in the region 3.5 < L < 4.0. Plasmaspheric hiss may thus also be a significant loss process in the inner region of the outer radiation belt during magnetically disturbed periods.Citation: Meredith, N. P., R. B. Horne, S. A. Glauert, and R. R. Anderson (2007), Slot region electron loss timescales due to plasmaspheric hiss and lightning-generated whistlers,