On the parameters affecting the characteristics of the “wired” glucose oxidase anode

Mano, Nicolas; Mao, Fei; Heller, Adam

doi:10.1016/j.jelechem.2004.08.014

Cited by 116 publications

(76 citation statements)

References 60 publications

(128 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The functions bound to the poly(4-vinylpyridine) backbone are randomly distributed. 178,180 reference glucose analyzer, showed a median absolute relative difference (ARD) of 9.3%. The percentage of the FreeStyle Navigator measurements that were in the clinically accurate Clarke error grid A zone was 81.7% and the percentage in the benign error grid B zone was 16.7%.…”

Section: Applications Of Glucose Oxidation Electrocatalysts Based On mentioning

confidence: 99%

Electrochemical Glucose Sensors and Their Applications in Diabetes Management

2008

Self Cite

View full text Add to dashboard Cite

About 6,000 peer reviewed articles have been published on electrochemical glucose assays and sensors, of which 700 were published in the 2005-2006 two-year period. Their number makes a full review of the literature, or even of the most recent advances, impossible. Nevertheless, this review should acquaint the reader with the fundamentals of the electrochemistry of glucose and provide a perspective of the evolution of the electrochemical glucose assays and monitors helping diabetic people, who constitute about 5% of the world's population. Because of the large number of diabetic people, no assay is performed more frequently than that of glucose. Most of these assays are electrochemical. The reader interested also in nonelectrochemical assays used in, or proposed for, the management of diabetes is referred to a 2007 review of Kondepati and Heise. 1 Adam Heller was born in 1933. Surviving the Holocaust, he arrived in Israel in 1945. He received his M.Sc. in Chemistry and Physics in 1957, then his PhD in Organic Chemistry in 1961 from Ernst David Bergman at the Hebrew University in Jerusalem. He postdoced at UC Berkeley (1962-3) and at Bell Laboratories . At GTE Labs (1964-1975 he built the first Nd 3+ liquid laser and, with J. J. Auborn, the still worldwide used Li/SOCl 2 battery. At Bell Labs (1975)(1976)(1977)(1978)(1979)(1980)(1981)(1982)(1983)(1984)(1985)(1986)(1987)(1988) he designed the first >10% efficient electrochemical solar cells and the first >10% efficient hydrogengenerating solar-powered photoelectrode. He also headed Bell Labs' Electronic Materials Research Department (1977)(1978)(1979)(1980)(1981)(1982)(1983)(1984)(1985)(1986)(1987)(1988), which developed part of the high density chip interconnection technology underlying the miniaturization of portable electronic devices. He was appointed to the Ernest Cockrell Sr. Chair in Engineering of the University of Texas at Austin in 1988, and in 2001 became one of UT's first Research Professors. At UT he pioneered the electrical wiring of enzymes. In 1996 he cofounded with his son Ephraim Heller TheraSense Inc., now part of Abbott Diabetes Care, to improve the lives of diabetic people. The company introduced in 2000 the blood sugar monitor FreeStyle, a thin-layer microcoulometer utilizing only 300 nL of blood, so little that it was, for the first time, painlessly obtained. In 2007 it provided for more than 1 billion painless glucose assays. After alleviating the pain of diabetes monitoring, FreeStyle Navigator, based on the electrical wiring of glucose oxidase, introduced in 2007 in Europe and Israel and in 2008 in the U.S., removed the worry of diabetic people by continuously monitoring their glucose levels. Heller aims his work at alleviating suffering through bioelectrochemistry.

show abstract

Section: Applications Of Glucose Oxidation Electrocatalysts Based On mentioning

confidence: 99%

Electrochemical Glucose Sensors and Their Applications in Diabetes Management

2008

Self Cite

View full text Add to dashboard Cite

show abstract

“…[2,3] The oxidation of the organic compound takes place at a bioanode [4] and the reduction of the oxygen takes place at a biocathode. [5] While the anode has been the subject of extensive research and development, [6] the performance of O2 reducing cathodes needs improvement.…”

Section: Introductionmentioning

confidence: 99%

Laccase cathode approaches to physiological conditions by local pH acidification

Clot

Gutiérrez-Sánchez

Shleev

et al. 2012

Electrochemistry Communications

View full text Add to dashboard Cite

show abstract

“…Previously, enzyme-based BFC made use of a variety of different combinations of oxidoreductases as biocomponent for the BFC anode such as e.g. glucose oxidase [13][14][15][16][17], NAD + -dependent glucose dehydrogenase [18,19], FAD-heme glucose dehydrogenase [20], PQQ-dependent glucose dehydrogenase [21,22], alcohol oxidase [12], quinohemoprotein alcohol dehydrogenase [23], NAD + -dependent alcohol dehydrogenase [24][25][26], fructose dehydrogenase [27] and hydrogenases [28][29][30]. For the biocathode mainly different laccases [5,16,31] or bilirubin oxidase [8, 25, 27, 32-35,] were used; however, also diaphorase [18,19,36] or a reconstituted cytochrome c-cytochrome oxidase couple [4,[37][38][39] were proposed.…”

Section: Introductionmentioning

confidence: 99%

Membrane‐Less Biofuel Cell Based on Cellobiose Dehydrogenase (Anode)/Laccase (Cathode) WiredviaSpecific Os‐Redox Polymers

et al. 2009

View full text Add to dashboard Cite

A membrane‐free biofuel cell (BFC) is reported based on enzymes wired to graphite electrodes by means of Os‐complex modified redox polymers. For the anode cellobiose dehydrogenase (CDH) is used as a biocatalyst whereas for the cathode a laccase was applied. This laccase is a high‐potential laccase and hence able to reduce O2 to H2O at a formal potential higher than +500 mV versus Ag/AgCl. In order to establish efficient electrochemical contact between the enzymes and graphite electrodes electrodeposition polymers containing Os‐complex with specifically designed monomer compositions and formal potentials of the coordinatively bound Os‐complex were synthesised and used to wire the enzymes to the electrodes. The newly designed CDH/Os‐redox polymer anode was characterised at different pH values and optimised with respect to the nature of the polymer and the enzyme‐to‐polymer ratio. The resulting BFC was evaluated running on β‐lactose as a fuel and air/O2 as an oxidising agent. The power output, the maximum current density and the electromotor force (Eemf) were found to be affected by the pH value, resulting in a maximum power output of 1.9 μW cm–2 reached at pH 4.3, a maximum current density of about 13 μA cm–2 at pH 3.5, and the highest Eemf approaching 600 mV at pH 4.0.

show abstract

On the parameters affecting the characteristics of the “wired” glucose oxidase anode

Cited by 116 publications

References 60 publications

Electrochemical Glucose Sensors and Their Applications in Diabetes Management

Electrochemical Glucose Sensors and Their Applications in Diabetes Management

Laccase cathode approaches to physiological conditions by local pH acidification

Membrane‐Less Biofuel Cell Based on Cellobiose Dehydrogenase (Anode)/Laccase (Cathode) WiredviaSpecific Os‐Redox Polymers

Contact Info

Product

Resources

About