We calculate the perihelion precession δ for nearly circular orbits in a central potential V (r). Differently from other approaches to this problem, we do not assume that the potential is close to the Newtonian one. The main idea in the deduction is to apply the underlying symmetries of the system to show that δ must be a function of r · V ′′ (r)/V ′ (r), and to use the transformation behaviour of δ in a rotating system of reference. This is equivalent to say, that the effective potential can be written in a one-parameter set of possibilities as sum of centrifugal potential and potential of the central force. We get the following universal formula valid for V ′ (r) > 0It has to be read as follows: a circular orbit at this value r exists and is stable if and only if this δ is a well-defined real; and if this is the case, then the angular difference from one perihelion to the next one for nearly circular orbits at this r is exactly 2π + δ(r). Then we apply this 1 result to examples of recent interest like modified Newtonian gravity and linearized fourth-order gravity.In the second part of the paper, we generalize this universal formula to static spherically symmetric space-timesfor orbits near r it reads− 1 and can be applied to a large class of theories.