On the potential of human sinus cavity diagnostics using diode laser gas spectroscopy

Persson, Linda; Svanberg, Katarina; Svanberg, Sune

doi:10.1007/s00340-005-1968-1

Cited by 35 publications

(34 citation statements)

References 9 publications

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“…[7] for the frontal sinuses, and in transmission geometry for the maxillary sinuses, as shown above. Actually, hybrids, where light is injected through the orbital wall close to the upper eye lid and the emerging light is detected against the forehead, or light is injected from the outside below the cheek bone and detected above the cheek bone have proved to be feasible, yielding strong signals, without the need of internal light injection.…”

Section: Discussionmentioning

confidence: 99%

“…In the first study, a faint oxygen signal could be observed in a backscattering geometry for the frontal sinuses of a healthy volunteer. 7 We have now explored the technique in a transmission geometry probing the maxillary (cheek) sinuses by injection of light using fibre optics in contact with the palate, and detecting the diffusely scattered light emerging out through the cheek bone. Strong signal differences in oxygen imprint between two volunteers with widely different anamnesis regarding maxillary sinus status were observed.…”

Section: -6mentioning

confidence: 99%

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Non-intrusive optical study of gas and its exchange in human maxillary sinuses

et al. 2007

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Non-intrusive optical study of gas and its exchange in human maxillary sinuses -art. no. 662804Persson, Linda; Andersson, Mats; Svensson, Tomas; Lewander, Märta; Svanberg, Katarina; Svanberg, Sune Lewander, M., Svanberg, K., & Svanberg, S. (2007). Non-intrusive optical study of gas and its exchange in human maxillary sinuses -art. no. 662804. In Diagnostic Optical Spectroscopy in Biomedicine IV (Vol. 6628, pp. 62804-62804). SPIE. DOI: 10.1117/12.728120 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal Volunteers have been investigated by injecting near-infrared light fibre-optically in contact with the palate inside the mouth. The multiply scattered light was detected externally by a handheld probe on and around the cheek bone. A significant signal difference in oxygen imprint was observed when comparing volunteers with widely different anamnesis regarding maxillary sinus status. Control measurements through the hand and through the cheek below the cheekbone were also performed to investigate any possible oxygen offset in the setup. These provided a consistently non-detectable signal level. The passages between the nasal cavity and the maxillary sinuses were also non-intrusively optically studied, to the best of our knowledge for the first time. These measurements provide information on the channel conductivity which may prove useful in facial sinus diagnostics.The results suggest that a clinical trial together with an ear-nose-throat (ENT) clinic should be carried out to investigate the clinical use of the new technique.

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Section: Discussionmentioning

confidence: 99%

Section: -6mentioning

confidence: 99%

Non-intrusive optical study of gas and its exchange in human maxillary sinuses

et al. 2007

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“…For the practical application of the method, measurements in back-scattering geometry (as already applied in our sinusitis monitoring [15]) is of great interest. In order to further elucidate the interplay between scattering and absorption, time-resolved measurements of the photon history in the wood for the two wavelengths would provide independent information on the scattering of the material and the liquid water contents.…”

Section: Conclusion and Discussionmentioning

confidence: 99%

“…Concentrations could be determined by combining GASMAS measurements with time-resolved measurement, revealing the time history of the photons inside the sample [14]. The GASMAS technique was also very recently applied to the monitoring of human sinus cavities [15].…”

Section: Introductionmentioning

confidence: 99%

Spectroscopic studies of wood-drying processes

Andersson¹,

Persson²,

Sjöholm³

et al. 2006

Opt. Express

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By the use of wavelength-modulation diode laser spectroscopy, water vapor and oxygen are detected in scattering media nonintrusively, at 980 nm and 760 nm, respectively. The technique demonstrated is based on the fact that free gases have extremely sharp absorption structures in comparison with the broad features of bulk material. Water vapor and oxygen measurements have been performed during the drying process of wood.The results suggest that the demonstrated technique can give information about the drying process of wood to complement that of commercially available moisture meters. In particular, the time when all the free water has evaporated from the wood can be readily identified by a strong falloff in the water vapor signal accompanied by the reaching of a high-level plateau in the molecular oxygen signal. Furthermore, the same point is identified in the differential optical absorption signal for liquid water, with a sharp increase by an order of magnitude in the ratio of the signal intensities at 980 nm and 760 nm.

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“…4,[6][7][8][9] Gas exchange dynamics has been studied by placing samples of wood and fruit in nitrogen atmospheres and monitoring the re-invasion of oxygen. 7,8 In this paper we show the potential of using GASMAS for determination of physical and structural parameters of pharmaceutical solids. We present results from a study of pharmaceutical tablets made from two different sieve fractions (particle size distributions) and with different compression forces.…”

Section: Introductionmentioning

confidence: 99%