1966 Help me understand this report
On the Role of Histamine Release and Mast Cell Damage in Rat Anaphylaxis
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Cited by 5 publications
(1 citation statement)
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“…In the pharmacological analysis of the mechanism of systemic anaphylaxis of the rat, no uniform conclusion has been reached [9,14,15,21,34,35]. Based on the observations that a) tissue mast cells are disrupted, b) a rise in plasma histamine occurs during anaphylaxis, and c) rats are protected against systemic anaphylaxis by pretreatment with either antihistamine drugs or the chemical histamine liberator, compound 48/80, M ota [21] concluded that histamine plays an important role in rat anaphylaxis.…”
Section: Discussionmentioning
confidence: 99%
“…In the pharmacological analysis of the mechanism of systemic anaphylaxis of the rat, no uniform conclusion has been reached [9,14,15,21,34,35]. Based on the observations that a) tissue mast cells are disrupted, b) a rise in plasma histamine occurs during anaphylaxis, and c) rats are protected against systemic anaphylaxis by pretreatment with either antihistamine drugs or the chemical histamine liberator, compound 48/80, M ota [21] concluded that histamine plays an important role in rat anaphylaxis.…”
Section: Discussionmentioning
confidence: 99%
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