This paper studies the nonlocal fractional analog of the famous paper of Brezis and Nirenberg [Comm. Pure Appl. Math. 36 (1983), no. 4, 437-477]. Namely, we focus on the following model:where (−Δ) 𝑠 is the fractional Laplace operator, 𝑠 ∈ (0, 1), with 𝑁 > 2𝑠, 2 < 𝑝 < 2 * 𝑠 , 𝛽 > 0, 𝜆, 𝛼 ∈ ℝ, and establish the existence of nontrivial solutions and sign-changing solutions for the problem ().