The integration of Distributed Energy Resources (DERs) into distribution systems greatly increases the system complexity and introduces two-way power flow. Conventional protection schemes are based upon local measurements and simple linear system models, and are thus not capable of handling the new complexity and power flow patterns in systems with high DER penetration. In this paper, we propose a data-driven protection framework to address the challenges introduced by DERs. Firstly, considering the limited available data under fault conditions, we adopt the Support Vector Data Description (SVDD) method, a commonly used one-class classifier, for distribution system fault detection, which only requires the normal data for its training process. Secondly, incremental learning is incorporated into the proposed SVDD-based protection framework to accommodate variations of the integration level of DERs in distribution systems over time. In particular, the artificial uniform-hyperspherical data generation model is incorporated into the incremental SVDD to boost the training speed. Finally, we validate the proposed method under the IEEE 123-node test feeder. Simulation results demonstrate that our proposed SVDD-based fault detection framework significantly improves the robustness and resilience against DERs in comparison with conventional protection systems. Meanwhile, the proposed online updating model outperforms the existing incremental SVDD models in terms of successful training speed.