One-minute and green synthesis of magnetic iron oxide nanoparticles assisted by design of experiments and high energy ultrasound: Application to biosensing and immunoprecipitation
“…The revealed that the prepared NC was spherical with an average size of 10-100 nm 4a,b). Following our study, Pérez-Beltrán et al ( 2021) [44] demonstrated that the vestigation of FeO NPs displayed a spherical shape. The elemental configur CS/FeO NC was identified by EDS analysis.…”
Chitosan (CS) functionalization over nanomaterials has gained more attention in the biomedical field due to their biocompatibility, biodegradability, and enhanced properties. In the present study, CS functionalized iron (II) oxide nanocomposite (CS/FeO NC) was prepared using Sida acuta leaf extract by a facile and eco-friendly green chemistry route. Phyto-compounds of S. acuta leaf were used as a reductant to prepare CS/FeO NC. The existence of CS and FeO crystalline peaks in CS/FeO NC was confirmed by XRD. FE-SEM analysis revealed that the prepared CS/FeO NC were spherical with a 10–100 nm average size. FTIR analyzed the existence of CS and metal-oxygen bands in the prepared NC. The CS/FeO NC showed the potential bactericidal activity against E. coli, B. subtilis, and S. aureus pathogens. Further, CS/FeO NC also exhibited the dose-dependent anti-proliferative property against human lung cancer cells (A549). Thus, the obtained outcomes revealed that the prepared CS/FeO NC could be a promising candidate in the biomedical sector to inhibit the growth of bacterial pathogens and lung cancer cells.
“…The revealed that the prepared NC was spherical with an average size of 10-100 nm 4a,b). Following our study, Pérez-Beltrán et al ( 2021) [44] demonstrated that the vestigation of FeO NPs displayed a spherical shape. The elemental configur CS/FeO NC was identified by EDS analysis.…”
Chitosan (CS) functionalization over nanomaterials has gained more attention in the biomedical field due to their biocompatibility, biodegradability, and enhanced properties. In the present study, CS functionalized iron (II) oxide nanocomposite (CS/FeO NC) was prepared using Sida acuta leaf extract by a facile and eco-friendly green chemistry route. Phyto-compounds of S. acuta leaf were used as a reductant to prepare CS/FeO NC. The existence of CS and FeO crystalline peaks in CS/FeO NC was confirmed by XRD. FE-SEM analysis revealed that the prepared CS/FeO NC were spherical with a 10–100 nm average size. FTIR analyzed the existence of CS and metal-oxygen bands in the prepared NC. The CS/FeO NC showed the potential bactericidal activity against E. coli, B. subtilis, and S. aureus pathogens. Further, CS/FeO NC also exhibited the dose-dependent anti-proliferative property against human lung cancer cells (A549). Thus, the obtained outcomes revealed that the prepared CS/FeO NC could be a promising candidate in the biomedical sector to inhibit the growth of bacterial pathogens and lung cancer cells.
“…Table 3 shows the values for magnetic parameters such as saturation magnetism, residual magnetism, and coercive force. The reduction in the saturation magnetism can be due to surface effects such as spin canting, the partial oxidation of the surface of the particles, shifting away from the stoichiometric state, and most importantly, the presence of the phases of impurity and the non-magnetic particles of these phases, affecting the value of this parameter (Yarie et al 2016 ; Venkateswarlu et al 2014 ; Elhamifar et al 2018 ; Pérez-Beltrán et al 2021 ). Fig.…”
The suitable structural characteristics of magnetic nanoparticles have resulted in their widespread use in magnetic hyperthermia therapy. Moreover, they are considered a proper and operational choice for pharmaceutical nanocarriers. Using the biomimetic method, we were able to produce iron oxide magnetic nanoparticles from the bacterial source of PTCC1250, Bacillus megaterium, for therangostic diagnosis systems and targeted drug delivery. Some of the benefits of this method include mitigated environmental and biological dangers, low toxicity, high biocompatibility, cheap and short-term mass production possibilities in each synthesis round compared to other biological sources, simple equipment required for the synthesis; and the possibility of industrial-scale production. Bacillus megaterium is a magnetotactic bacteria (MTB) that has a magnetosome organelle capable of orienting based on external magnetic fields, caused by the mineralization of magnetic nanocrystals. Utilizing this capability and adding an iron nitrate solution to the bacterial suspension, we synthesized iron oxide nanoparticles. The extent of synthesis was measured using UV–visible spectrophotometry. The morphology was evaluated using FESEM. The crystallized structure was characterized using RAMAN and XRD. The size and distribution of the nanoparticles were assessed using DLS. The surface charge of the nanoparticles was measured using zeta potential. The synthesis of iron oxide nanoparticles was confirmed using FT-IR, and the magnetic property was measured using VSM. This study is continued to identify industrial and clinical applications.
“…SEM is the leading tool that is capable of achieving a detailed visual image of a particle with high-quality and spatial resolution of 1 nm (Brabazon and Raffer, 2010;Akhtar et al, 2018 ). Pérez-Beltrán et al (2021) demonstrated that The SEM investigation of FeONPs displayed a spherical shaped particle. Hebzi and Helen (2020) stated that iron oxide nanoparticles synthesized from crustacean waste crab shells showed the scanning electrons microscopic image which showed the high density of iron oxide nanoparticles synthesized by chitosan.…”
The present investigation was aimed to develop an easy, low-cost and eco-friendly method for the synthesis of Chitosan based iron oxide Nanoparticles (Cs-FeNPs) using shells of Penaeus monodon. The synthesized Cs-FeNPs were characterized by using Ultraviolet-Visible spectroscopy (UV), Fourier-Transform Infrared spectroscopy (FT-IR), X-ray Diffraction (XRD), Transmission Electron Microscope (HR-TEM) and Scanning Electron Microscope (SEM with EDAX). The visible dark black color formation and surface plasmon resonance at 233 nm indicates the biosynthesis of Cs-FeNPs. The TEM images showed polydispersal, and spherical Cs-FeNPs particle size of 3 to 5 nm. Antibacterial activity of chitosan aqueous extract and Cs-FeNPs showed an excellent activity against Gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) and Gram-negative bacteria (Escherichia coli, Enterobacter, Klebsiella pneumoniae and Pseudomonas aeruginosa).
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