One‐pot photoinduced synthesis of dansyl containing acrylamide hydrogels and their chemosensing properties

Abstract

Novel fluorescent acrylamide hydrogel containing dansyl moiety (DNS‐gel) was synthesized via free‐radical photopolymerization of acrylamide/N,N′‐methylenebisacrylamide by using dansyl chloride as a photoinitiator. DNS‐gel presented dual‐fluorescence emission when excited at 344 nm in acetonitrile:water (1:1) solvent system due to twisted intramolecular charge transfer between dimethylamino and naphthalene units in the dansyl moiety. Synthesized fluorophore containing gel was utilized as a fluorescent sensor against specific metal ions (Pb2+, Hg2+, Co2+, Cd2+, Mn2+, and Zn2+) and nitroaromatic compounds [1,2‐dinitrobenzene, 2,4,6‐trinitro‐1‐phenol [picric acid (PA)], 4‐nitrophenol, 2,4,6‐trinitrotoluene, 2,4‐dinitrophenol (2,4‐DNP), and 2‐nitrotoluene]. Fluorescence intensity of DNS‐gel was diminished by degrees upon the infusion of metal ions and nitroaromatics. For all compounds, the greatest quenching effectiveness was attained in the presence of Co2+ (72.56%), PA (88.55%), and 2,4‐DNP, suggesting that DNS‐gel could be employed as a potential Co2+, PA, and 2,4‐DNP chemical probes. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47096.

Design, Bioanalytical, and Biomedical Applications of Aptamer-Based Hydrogels

“…A variety of physical and chemical changes of the hydrogel, including volume change and sol-gel transition, are particularly sensitive to specific external stimuli due to their component materials (18)(19)(20)(21). These stimuli-responsive hydrogels have gained immense consideration because of their potential in drug delivery systems (22)(23)(24)(25)(26), sensors (27)(28)(29)(30)(31)(32), cancer therapy (33)(34)(35)(36)(37), cell culture substrates (38-40), and tissue engineering (38,(41)(42)(43)(44). Beyond these stimulants, many specific biomolecules, such as antibodies, nucleic acids (or DNA), and enzymes, that can rapidly respond to target analytes are used for functional materials to modify polymers in order to construct target-responsive hydrogels (45,46).…”