One-step enrichment of phenolics from Chaenomeles speciosa (Sweet) Nakai fruit using macroporous resin: Adsorption/desorption characteristics, process optimization and UPLC-QqQ-MS/MS-based quantification

Hou, Mengyang; Lin, Chengyuan; Ma, Yanhua; Shi, Jingchun; Liu, Jie; Zhu, Lin; Bian, Zhaoxiang

doi:10.1016/j.foodchem.2023.138085

Cited by 8 publications

(5 citation statements)

References 38 publications

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“…Furthermore, the desorption ability of HPD-300 was significantly higher than that of HPD-100, indicating that paeonol was more easily desorbed from the resin with a large specific surface area and pore size [15]. The results are consistent with the findings reported by previous research [23]. Thus, the HPD-300 macroporous resin was selected to purify paeonol from MC, followed by the optimization of the purification condition.…”

Section: Purification Of Paeonol From MC By Macroporous Resin Adsorpt...supporting

confidence: 87%

“…Thus, peak 4 was characterized as paeonol. The molecular formula of peak 5 was designed as C 23 The identification of paeoniflorin was consistent with a previous report [61]. Compared with peak 1, the fragment ions at m/z 171.0287 and m/z 169.0136 were observed, which indicated that compound 6 was a derivative of gallic acid.…”

Section: Compositional Analysis Of MC Extractsupporting

confidence: 86%

“…Thus, ultrasound-assisted ethanol extraction is a suitable technique for the extraction of paeonol. Natural phenolic compounds are usually purified by resin adsorption [23], recrystallisation, column chromatography [24], high-speed counter-current chromatography [25], preparative high-performance liquid chromatography [26], etc. At present, the purification methods of paeonol are mainly focused on recrystallization and high-speed countercurrent chromatography [27].…”

Section: Introductionmentioning

confidence: 99%

“…However, it is subject to special demands on technique, resulting in longer operating recycling, a large amount organic solvent consumption, and high costs [30]. Macroporous adsorption resin is a type of organic polymeric absorbent with physicochemical properties that are inexpensive, readily available, and have excellent selectivity [23]. Comparatively, the macroporous resin adsorption method seems to be the most suitable method due to its low cost, low solvent consumption, and environment friendliness [23,31].…”

Section: Introductionmentioning

confidence: 99%

“…Macroporous adsorption resin is a type of organic polymeric absorbent with physicochemical properties that are inexpensive, readily available, and have excellent selectivity [23]. Comparatively, the macroporous resin adsorption method seems to be the most suitable method due to its low cost, low solvent consumption, and environment friendliness [23,31]. At present, it has been widely applied for the purification of bioactive components, such as flavonoid [32][33][34], polyphenol [35][36][37][38][39][40], and monoterpene glycoside [41][42][43]; however, there is no report on using macroporous adsorption resin to purify paeonol from MC.…”

Section: Introductionmentioning

confidence: 99%

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Ultrasound-Assisted Extraction of Paeonol from Moutan Cortex: Purification and Component Identification of Extract

Meng,

Chen,

Zheng

et al. 2024

Molecules

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Moutan Cortex (MC) is a traditional Chinese medicine that contains abundant medicinal components, such as paeonol, paeoniflorin, etc. Paeonol is the main active component of MC. In this study, paeonol was extracted from MC through an ultrasound-assisted extraction process, which is based on single-factor experiments and response surface methodology (RSM). Subsequently, eight macroporous resins of different properties were used to purify paeonol from MC. The main components of the purified extract were identified by ultra-performance liquid chromatography–quadrupole–time of flight–mass spectrometry (UPLC-Q-TOF-MS/MS). The results indicate the optimal parameters are as follows: liquid-to-material ratio 21:1 mL/g, ethanol concentration 62%, ultrasonic time 31 min, ultrasonic temperature 36 °C, ultrasonic power 420 W. Under these extraction conditions, the actual yield of paeonol was 14.01 mg/g. Among the eight tested macroporous resins, HPD-300 macroporous resin was verified to possess the highest adsorption and desorption qualities. The content of paeonol increased from 6.93% (crude extract) to 41.40% (purified extract) after the HPD-300 macroporous resin treatment. A total of five major phenolic compounds and two principal monoterpene glycosides were characterized by comparison with reference compounds. These findings will make a contribution to the isolation and utilization of the active components from MC.

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Section: Purification Of Paeonol From MC By Macroporous Resin Adsorpt...supporting

confidence: 87%

Section: Compositional Analysis Of MC Extractsupporting

confidence: 86%