One-step preparation of nitrogen-doped graphenequantum dots from oxidized debris of graphene oxide

Abstract

Highly blue-luminescent nitrogen-doped graphene quantum dots (N-GQDs) are obtained by hydrothermal treatment of graphene oxide in the presence of ammonia. The yield of N-GQDs is about 8.7% in weight. A high quantum yield of maximum 24.6% at an excitation wavelength of 340 nm is achieved. They are applied for bioimaging of HeLa cells, and showed bright luminescence and excellent biocompatibility.

Ultrafast ammonia-driven, microwave-assisted synthesis of nitrogen-doped graphene quantum dots and their optical properties

“…multistep method and one-step method. Multistep methods usually require the synthesis of graphene oxide (GO), reduced GO (rGO), or GQDs first, and then nitrogen doping is performed by electrochemical generation [8], hydrothermal methods [12,13,[15][16][17][18], or high-temperature treatment [11]. Some of these methods need further chemical tailoring to cut nitrogen-doped graphene into NGQDs [11,18].…”

Nanofabrication of Graphene Quantum Dots with High Toxicity Against Malaria Mosquitoes, Plasmodium falciparum and MCF-7 Cancer Cells: Impact on Predation of Non-target Tadpoles, Odonate Nymphs and Mosquito Fishes

“…The synthetic process is cheap and relatively simple without the help of strong acid to cut large graphene oxide. Furthemore, the synthesis was in aqueous solution and the product yield is about 34.8 % in weight, higher than the other reported GQD synthesis routes [8,60].…”

“…This interaction helps GQDs to decrease the cell viability by alterations in the nuclear morphology, cytoplasm organization, and changes in gene expression of MCF-7 cells. Nitrogen-doped GQDs were co-cultured with HeLa cells and did not showed considerable toxicity on HeLa cells by 3-(4, 5-dimeth-ylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide test (MTT) assay [60], see also [70]. To our mind, GQDs are a possible candidate to inhibit tumor progression and thereby effectively controlling the disease progression without toxicity towards normal cells.…”

Preparation of sulfonated reduced graphene oxide by radiation-induced chemical reduction of sulfonated graphene oxide

“…In the SGO spectrum, the characteristic peak corresponding to the chemical structure of sulfanilic acid was clearly observed at 1260 cm -1 (O=S=O), although the peaks for the amide and phenyl groups hidden by the GO could not be observed [17]. On the other hand, the oxygen-containing functionalities such as -OH, C=O, and C-OH were reduced with an increase in the absorbed dose [18]. [19].…”