One-year follow-up changes in weight are associated with changes in blood pressure in young Mexican adults

Andrade, Flávia Cristina Drumond; Vázquez-Vidal, Itzel; Flood, Tracy; Aradillas‐García, Celia; Vargas-Morales, Juan Manuel; Medina-Cerda, Eduardo; Terán-García, Margarita

doi:10.1016/j.puhe.2012.02.005

Cited by 13 publications

(9 citation statements)

References 27 publications

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“…However, despite these differences and the very wide range of weight gain reported in these studies, approximately a 6-pound gain as the modal yearly weight gain, not 15 pounds was shown. It is also evident from Figure 2 that the vast majority of published studies observe a positive weight gain 204-208 , although several studies failed to find a significant weight gain 176,205,209,210 .…”

Section: Introductionmentioning

confidence: 90%

Weighing the Evidence of Common Beliefs in Obesity Research

Casazza

Brown

Astrup

et al. 2014

Critical Reviews in Food Science and Nutrition

155

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Obesity is a topic on which many views are strongly held in the absence of scientific evidence to support those views, and some views are strongly held despite evidence to contradict those views. We refer to the former as “presumptions” and the latter as “myths”. Here we present nine myths and ten presumptions surrounding the effects of rapid weight loss; setting realistic goals in weight loss therapy; stage of change or readiness to lose weight; physical education classes; breast-feeding; daily self-weighing; genetic contribution to obesity; the “Freshman 15”; food deserts; regularly eating (versus skipping) breakfast; eating close to bedtime; eating more fruits and vegetables; weight cycling (i.e. yo-yo dieting); snacking; built environment; reducing screen time in childhood obesity; portion size; participation in family mealtime; and drinking water as a means of weight-loss. For each of these, we describe the belief and present evidence that the belief is widely held or stated, reasons to support the conjecture that the belief might be true, evidence to directly support or refute the belief, and findings from randomized controlled trials, if available. We conclude with a discussion of the implications of these determinations, conjecture on why so many myths and presumptions exist, and suggestions for limiting the spread of these and other unsubstantiated beliefs about obesity domain.

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Section: Introductionmentioning

confidence: 90%

Weighing the Evidence of Common Beliefs in Obesity Research

Casazza

Brown

Astrup

et al. 2014

Critical Reviews in Food Science and Nutrition

155

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show abstract

“…Briefly, a total of 10,000 samples and validated self-administered food frequency questionnaires (FFQ) for the Mexican population were recollected from volunteers in 2009 at the UASLP in Mexico [23]. A detailed description of the data collection and phenotypes of the subjects participating in the UP-AMIGOS cohort study has been published previously [20, 21]. As previously described [21, 22], > 10,000 individuals were recruited and screened for this multidisciplinary investigation, and only 998 were found eligible on the basis of the selection criteria with completed demographics, lipid profiles, and genetic data.…”

Section: Methodsmentioning

confidence: 99%

“…A single case/control study conducted in Mexican adults identified FADS3 as a causal gene for familial combined hyperlipidemia and elevated TG, but variants in other genes of this cluster ( FADS1/FADS2 ) and associations with blood lipids have not been studied in healthy young Mexicans who may be at risk for the development of dyslipidemia due to genetic predisposition [20]. Therefore, the aim of this study was to establish associations between 6 variants in the FADS gene cluster (rs174546, rs1535, rs174548, rs174550, rs174450, and rs174618) and serum lipid profiles in young Mexicans in the UP-AMIGOS cohort study [21, 22]. …”

Section: Introductionmentioning

confidence: 99%

Serum Lipid Concentrations and FADS Genetic Variants in Young Mexican College Students: The UP-AMIGOS Cohort Study

Vázquez-Vidal¹,

Voruganti²,

Hannon³

et al. 2018

Lifestyle Genomics

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Background: Recent genome-wide association studies in the Mexican population have identified several genetic loci associated with blood lipid levels in adults. However, studies focusing on the fatty acid desaturase (FADS) gene cluster have been understudied in this population, even though it seems associated with lipid profiles in other ethnicities. The aim of this study was to test associations between single nucleotide polymorphisms (SNPs) in the FADS cluster (rs174546, rs1535, rs174548, rs174550, rs174450, and rs174618) and serum lipid profiles in young Mexicans. Methods: Anthropometrics, serum lipid profiles, and FADS SNPs were measured in 998 subjects in the UP-AMIGOS cohort study. Genotype-phenotype (total cholesterol [TC], triglyceride [TG], high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], and very-low-density lipoprotein [VLDL]) associations were assessed using PLINK adjusted for sex, age, and body mass index (BMI). Results: Among 6 FADS SNPs, we found that carriers of the C-allele of the FADS1-rs174546 showed a significant association with lower TG concentrations (β = –12.6 mg/dL, p = 0.009) and lower VLDL concentrations (β = –2.52 mg/dL, p = 0.005). We found that rs174546, rs1535, and rs174550 were in high linkage disequilibrium (r² > 0.80). There were no significant associations between rs174550, rs174548, and rs174618 and lipid profiles. Conclusion: A genetic variant in the FADS1 (rs174546) gene is a major contributor of plasma TG and VLDL concentrations in healthy young Mexicans.

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“…Change in BMI was calculated as BMI in 2006 minus the BMI at baseline. This difference was divided by the baseline BMI and then recoded into three categories: (a) an increase of 5% or more; (b) a decrease of 5% or more; and (c) changes within 5% of the baseline weight (reference category) [19, 39]. …”

Section: Methodsmentioning

confidence: 99%

The Impact of Body Mass Index and Weight Changes on Disability Transitions and Mortality in Brazilian Older Adults

Andrade

Nazan

Lebrão

et al. 2013

Journal of Aging Research

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The aim of this study was to examine the association between body mass index and weight changes on disability transitions and mortality among Brazilian older adults. Longitudinal data from the Health, Well-Being, and Aging in Latin America and the Caribbean Study conducted in São Paulo, Brazil (2000 and 2006), were used to examine the impact of obesity on disability and mortality and of weight changes on health transitions related to disability. Logistic and multinomial regression models were used in the analyses. Individuals who were obese were more likely than those of normal weight to have limitations on activities of daily living (ADL), instrumental activity of daily living (IADL), and Nagi's limitations. Obesity was associated with higher incidence of ADL and IADL limitations and with lower recovery from Nagi's limitations. Compared to those who maintained their weight, those who gained weight experienced higher incidence of ADL and Nagi's limitations, even after controlling for initial body mass index. Higher mortality among overweight individuals was only found when the reference category was “remaining free of Nagi limitations.” The findings of the study underline the importance of maintaining normal weight for preventing disability at older ages.

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One-year follow-up changes in weight are associated with changes in blood pressure in young Mexican adults

Cited by 13 publications

References 27 publications

Weighing the Evidence of Common Beliefs in Obesity Research

Weighing the Evidence of Common Beliefs in Obesity Research

Serum Lipid Concentrations and FADS Genetic Variants in Young Mexican College Students: The UP-AMIGOS Cohort Study

The Impact of Body Mass Index and Weight Changes on Disability Transitions and Mortality in Brazilian Older Adults

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