Sparse inner product (SIP) has the attractive property of overhead being dominated by the intersection of inputs between parties, independent of the actual input size. It has intriguing prospects, especially for boosting machine learning on large-scale data, which is tangled with sparse data. In this paper, we investigate privacy-preserving SIP problems that have rarely been explored before. Specifically, we propose two concrete constructs, one requiring offline linear communication which can be amortized across queries, while the other has sublinear overhead but relies on the more computationally expensive tool. Our approach exploits state-of-the-art cryptography tools including garbled Bloom filters (GBF) and Private Information Retrieval (PIR) as the cornerstone, but carefully fuses them to obtain non-trivial overhead reductions. We provide formal security analysis of the proposed constructs and implement them into representative machine learning algorithms including k-nearest neighbors, naive Bayes classification and logistic regression. Compared to the existing efforts, our method achieves 2-50× speedup in runtime and up to 10× reduction in communication.