“…); (4) negative and positive feedbacks stabilizing the parameters of the gene network at a certain level, or, on the contrary, deviating them from the initial value, providing a transition to a new functional state [2]. Reconstruction of gene networks and deciphering their connectivity structure provide methodological basis for modern systems biology [3]. this review (1) introduces the concepts of Gene networks and related terms used in the post-genomic era (Gene regulatory networks (GRNs), transcription regulatory networks (tRNs), protein-protein interaction (PPI) networks, associative gene networks, etc.…”