This paper analyzes the mutual influence mechanism between vocational education and open education based on the development of the information age. Secondly, it constructs the coupling evaluation mode, uses the comprehensive development level test model to measure the value of the comprehensive development level of the regional system, and quantitatively analyzes the interactions between multiple systems through the coupling degree model. Then, the gray correlation model and entropy value method are used to test and analyze vocational education and open education. Finally, the empirical analysis of the coupling development of vocational education and open education. From the time analysis of the coupling coordination degree, the average value of the coupling coordination degree of vocational education and open education across the country was 0.18432 in 2010 and 0.35384 in 2020, with an overall increase of 0.16952, 91.97%, which is a significant increase. As a result, the coupling development mechanism of vocational education and open education adapts to the current needs of economic development and individual enhancement, prompting self-improvement and sustainable development of education.