Open-heart repair of ventricular septal defect in infancy by means of surface-induced hypothermia and coronary perfusion

Surface induced deep hypothermia combined with cardiopulmonary bypass (combined method) is excellent in open heart surgery of infants which combines each advantage of cardiopulmonary bypass and hypothermia. The present study was performed to investigate pathophysiological changes, especially metabolic changes, in combined method induced by two stressors such as cardiopulmonary bypass and hypothermia. In general, metabolic changes during hypothermia are temporarily enhanced immediately after the start of cardiopulmonary bypass. Lactacidemia and metabolic acidosis are rapidly improved after the start of perfusion rewarming, but abnormality of ceruloplasmin and cholesterol metabolism in the liver and hypopotassemia are not rapidly improved. Therefore, the treatment for these metabolic abnormalities seems to be necessary during and after the procedure.

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Metabolic changes in surface-induced deep hypothermia combined with cardiopulmonary bypass for cardiac surgery

Shida

Morimoto

Seki

et al. 1975

The Japanese Journal of Surgery

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Surgical Treatment of Large Ventricular Septal Defect with Pulmonary Hypertension in the First 24 Months of Life

Suzuki

Ishizawa

Tanaka

et al. 1976

The Annals of Thoracic Surgery

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Deep Hypothermia in Cardiovascular Surgery

Rittenhouse¹,

Mohri²,

Dillard³

et al. 1974

The Annals of Thoracic Surgery

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Open-heart repair of ventricular septal defect in infancy by means of surface-induced hypothermia and coronary perfusion

Cited by 3 publications

References 8 publications

Metabolic changes in surface-induced deep hypothermia combined with cardiopulmonary bypass for cardiac surgery

Metabolic changes in surface-induced deep hypothermia combined with cardiopulmonary bypass for cardiac surgery

Surgical Treatment of Large Ventricular Septal Defect with Pulmonary Hypertension in the First 24 Months of Life

Deep Hypothermia in Cardiovascular Surgery

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