Open source 3D-printed 1000 μL micropump

Bravo-Martínez, Jorge

doi:10.1016/j.ohx.2017.08.002

Cited by 21 publications

(17 citation statements)

References 10 publications

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“…This has resulted in an explosion of open-source digitally fabricated instruments and a repository of designs housed at the NIH [5,6,23,24]. There are many examples of progressively more sophisticated open-source 3-D printed parts being used to build chemical mixing systems [22][23][24][25], mechanical components for optics setups [26][27][28][29][30][31] and microscopes [32][33][34], instruments to test water quality testing [35][36][37][38], various types of syringe pumps [39][40][41][42][43] that are combined with other components to make complete systems for making microfluidics and metafluidics [44][45][46][47]. Although the most important features of open-source 3-D printable instruments is the ease with which scientists can customize a tool, in general, they are also much less expensive than equivalent (and often technically inferior) commercial proprietary systems [6,23,24,[48][49][50] and provide a high return on investment [51,52].…”

Section: Introductionmentioning

confidence: 99%

Open-Source Digitally Replicable Lab-Grade Scales

Hubbard

Pearce

2020

Instruments

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This study provides designs for a low-cost, easily replicable open-source lab-grade digital scale that can be used as a precision balance. The design is such that it can be manufactured for use in most labs throughout the world with open-source RepRap-class material extrusion-based 3-D printers for the mechanical components and readily available open-source electronics including the Arduino Nano. Several versions of the design were fabricated and tested for precision and accuracy for a range of load cells. The results showed the open-source scale was found to be repeatable within 0.05 g with multiple load cells, with even better precision (0.005 g) depending on load cell range and style. The scale tracks linearly with proprietary lab-grade scales, meeting the performance specified in the load cell data sheets, indicating that it is accurate across the range of the load cell installed. The smallest load cell tested (100 g) offers precision on the order of a commercial digital mass balance. The scale can be produced at significant cost savings compared to scales of comparable range and precision when serial capability is present. The cost savings increase significantly as the range of the scale increases and are particularly well-suited for resource-constrained medical and scientific facilities.

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Section: Introductionmentioning

confidence: 99%

Open-Source Digitally Replicable Lab-Grade Scales

Hubbard

Pearce

2020

Instruments

View full text Add to dashboard Cite

show abstract

“…This has resulted in an explosion of open source digitally fabricated instruments and a repository of designs housed at the NIH [5,6,23,24]. There are many examples of progressively more sophisticated open source 3-D printed parts being used to build chemical mixing systems [22][23][24][25], mechanical components for optics setups [26][27][28][29][30][31] and microscopes [32][33][34], instruments to test water quality testing [35][36][37][38], various types of syringe pumps [39][40][41][42][43] that are combined with other components to make complete systems for making microfluidics and metafluidics [44][45][46][47]. Although the most important features of open source 3-D printable instruments is the ease with which scientists can customize a tool, in general, they are also much less expensive than equivalent (and often technically inferior) commercial proprietary systems [6,23,24,[48][49][50] and provide a high return on investment [51,52].…”

Section: Introductionmentioning

confidence: 99%

Open Source Digitally Replicable Lab-Grade Scales

Hubbard¹,

Pearce²

2020

Preprint

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This study provides designs for a low-cost, easily replicable open source lab-grade digital scale that can be used as a precision balance. The design is such that it can be manufactured for use in most labs throughout the world with open source RepRap-class material extrusion-based 3-D printers for the mechanical components and readily available open source electronics including the Arduino Nano. Several versions of the design were fabricated and tested for precision and accuracy for a range of load cells. The results showed the open source scale was found to be repeatable within 0.1g with multiple load cells, with even better precision (0.01g) depending on load cell range and style. The scale tracks linearly with proprietary lab-grade scales, meeting the performance specified in the load cell data sheets, indicating that it is accurate across the range of the load cell installed. The smallest loadcell tested(100g) offers precision on the order of a commercial digital mass balance. The scale can be produced at significant cost savings compared to scales of comparable range and precision when serial capability is present. The cost savings increase significantly as the range of the scale increases and are particularly well-suited for resource-constrained medical and scientific facilities.

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“…Many open source digitally fabricated devices are now widely used by the scientific community [18][19][20]. For example, 3-D printed parts are used in chemical mixing [2,[20][21][22][23][24], optical and mechanical testing [24][25][26], water quality testing [27][28][29][30], and syringe pumping [31][32][33][34] (which can be in turn used for more complicated systems such as fabricating microfluidics and metafluidics [35][36][37] or slot die deposition [38]). In addition to offering scientists the ability to customize their equipment and fully control their function, open source 3-D printable tools are much less expensive than equivalent or inferior commercial systems [18,39,40].…”

Section: Introductionmentioning

confidence: 99%

Open Source Completely 3-D Printable Centrifuge

2019

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Centrifuges are commonly required devices in medical diagnostics facilities as well as scientific laboratories. Although there are commercial and open source centrifuges, the costs of the former and the required electricity to operate the latter limit accessibility in resource-constrained settings. There is a need for low-cost, human-powered, verified, and reliable lab-scale centrifuges. This study provides the designs for a low-cost 100% 3-D printed centrifuge, which can be fabricated on any low-cost RepRap-class (self-replicating rapid prototyper) fused filament fabrication (FFF)- or fused particle fabrication (FPF)-based 3-D printer. In addition, validation procedures are provided using a web camera and free and open source software. This paper provides the complete open source plans, including instructions for the fabrication and operation of a hand-powered centrifuge. This study successfully tested and validated the instrument, which can be operated anywhere in the world with no electricity inputs, obtaining a radial velocity of over 1750 rpm and over 50 N of relative centrifugal force. Using commercial filament, the instrument costs about U.S. $25, which is less than half of all commercially available systems. However, the costs can be dropped further using recycled plastics on open source systems for over 99% savings. The results are discussed in the context of resource-constrained medical and scientific facilities.

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Open source 3D-printed 1000 μL micropump

Cited by 21 publications

References 10 publications

Open-Source Digitally Replicable Lab-Grade Scales

Open-Source Digitally Replicable Lab-Grade Scales

Open Source Digitally Replicable Lab-Grade Scales

Open Source Completely 3-D Printable Centrifuge

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