The light yield and decay constant of BGO weremeasured at both dry ice and liquid nitrogen temperatures using two SiPMs directly coupled to a 6×6×6 cm2 cubic BGO crystal. With the measured light yield (5.2±0.3 PE/keV at dry ice temperature and 10.5±0.4 PE/keV at liquid nitrogen temperature) and decay constants, potential applications of BGO in ToF-PET and SPECT were discussed.