“…In case of traumatic tissue loss, half of the scortal sac can be reconstructed from the remaining scrotal tissue [ 11 ], which is highly similar to the wound healing characteristics of the spiny mouse Acomys [ 54 ]. Furthermore, excess skin is useful for defect coverage of the penile shaft in obese men [ 55 , 56 ], after trauma [ 57 ] or tumor excision [ 30 , 57 ] or for genital reassignment surgery [ 58 ]. Of note, skin adjacent to the outer genitalia, e.g., groin, suprapubic or perineal skin in the vicinity of the thigh, have a tendency to excessive scarring, whereas hypertrophic scarring is rarely found in genital skin [ 15 ].…”